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7-Ketocholesterol is a major oxidation product of cholesterol found in human atherosclerotic plaque and is more atherogenic than cholesterol in some animal studies. 7-Ketocholesterol can inhibit cholesterol 7alpha-hydroxylase, the rate-limiting step in bile acid biosynthesis, as well as strongly inhibiting HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis.
7KC; 7-KC; 7KC-Modified KLH
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg
100 µg