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The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line.
Aatk; AATYK; aatyk1; apoptosis associated tyrosine kinase; apoptosis-associated tyrosine kinase; apoptosis-associated tyrosine kinase 1B; brain apoptosis-associated tyrosine kinase; CDK5-binding protein; KIAA0641; Lemur tyrosine kinase 1; LMR1; LMTK1; mKIAA0641; p35-binding protein; p35BP; PPP1R77; protein phosphatase 1, regulatory subunit 77; serine/threonine-protein kinase LMTK1
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