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The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
1200005B17Rik; ABC; ABC14; ABCB6; ATG9 autophagy related 9 homolog A; ATP binding cassette subfamily B member 6; ATP binding cassette subfamily B member 6 (Langereis blood group); ATP-binding cassette half-transporter; ATP-binding cassette sub-family B member 6, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 6; ATP-binding cassette, sub-family B (MDR/TAP), member 6; ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group); ATP-binding cassette, sub-family B, member 6; DUH3; EST45597; FLJ22414; LAN; LOW QUALITY PROTEIN: ATP-binding cassette sub-family B member 6, mitochondrial; MCOPCB7; Mitochondrial ABC transporter 3; mitochondrial ATP-binding cassette sub-family B member 6; mt-ABC transporter 3; MTABC3; P-glycoprotein-related protein; PRP; PSHK2; ubiquitously-expressed mammalian ABC half transporter; Umat
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