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ANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals.
Ank; ANKH; ANKH inorganic pyrophosphate transport regulator; ankylosis, progressive homolog; CCAL2; CMDJ; CPPDD; D15Ertd221e; FLJ27166; fn54 protein; HANK; KIAA1581; MANK; mKIAA1581; progessive ankylosis-like protein; progressive ankylosis; progressive ankylosis homolog; progressive ankylosis protein; Progressive ankylosis protein homolog; UNQ241/PRO274
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