Antibodies that detect CD33 can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target CD33 in Human, Mouse, Non-human primate, Rat and Cynomolgus Monkey samples. Our CD33...Antibodies that detect CD33 can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target CD33 in Human, Mouse, Non-human primate, Rat and Cynomolgus Monkey samples. Our CD33 monoclonal, polyclonal and...Antibodies that detect CD33 can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target CD33 in Human, Mouse, Non-human primate, Rat and Cynomolgus Monkey samples. Our CD33 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Rat and Alpaca. These antibodies have been verified by Cell treatment and Knockout to confirm specificity to CD33. Find the CD33 antibody that fits your needs. Choose from 1 of 149 CD33 antibodies, which have been validated in experiments with 255 publications and 394 images featured in our data gallery.
Browse primary antibodies for WB,...
Antibodies that detect CD33 can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target CD33 in Human, Mouse, Non-human primate, Rat and Cynomolgus Monkey samples. Our CD33 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Rat and Alpaca. These antibodies have been verified by Cell treatment and Knockout to confirm specificity to CD33. Find the CD33 antibody that fits your needs. Choose from 1 of 149 CD33 antibodies, which have been validated in experiments with 255 publications and 394 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, and these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. Further, CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells. CD33 is also expressed on, and is a useful marker for, peripheral monocytes. CD33 is useful for distinguishing myelogenous leukemia cells from lymphoid or erythroid leukemias. Diseases associated with CD43 dysfunction include gallbladder lymphoma and extracutaneous mastocytoma.
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party
scientific content. Neither the content nor the BenchSci technology and processes for
selection have been evaluated by us; we are providing them as-is and without warranty of any kind,
including for use or application of the Thermo Fisher Scientific products presented.