Antibodies that detect CD83 can be used in several scientific applications, including Flow Cytometry, Western Blot, ELISA, Immunohistochemistry and Immunocytochemistry. These antibodies target CD83 in Human, Mouse, Rat and Non-human primate samples. Our CD83 monoclonal, polyclonal and...Antibodies that detect CD83 can be used in several scientific applications, including Flow Cytometry, Western Blot, ELISA, Immunohistochemistry and Immunocytochemistry. These antibodies target CD83 in Human, Mouse, Rat and Non-human primate samples. Our CD83 monoclonal, polyclonal and recombinant monoclonal...Antibodies that detect CD83 can be used in several scientific applications, including Flow Cytometry, Western Blot, ELISA, Immunohistochemistry and Immunocytochemistry. These antibodies target CD83 in Human, Mouse, Rat and Non-human primate samples. Our CD83 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Rat and Goat. These antibodies have been verified by Relative expression to confirm specificity to CD83. Find the CD83 antibody that fits your needs. Choose from 1 of 49 CD83 antibodies, which have been validated in experiments with 156 publications and 109 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other...
Antibodies that detect CD83 can be used in several scientific applications, including Flow Cytometry, Western Blot, ELISA, Immunohistochemistry and Immunocytochemistry. These antibodies target CD83 in Human, Mouse, Rat and Non-human primate samples. Our CD83 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Rat and Goat. These antibodies have been verified by Relative expression to confirm specificity to CD83. Find the CD83 antibody that fits your needs. Choose from 1 of 49 CD83 antibodies, which have been validated in experiments with 156 publications and 109 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
CD83 cell surface antigen is a 40-45kD glycoprotein expressed by peripheral blood dendritic cells. Peripheral lymphocytes can be induced to express very low levels of CD83 after culture in agents such as Con A or PHA. In immunohistology, CD83 is shown to be expressed strongly by interfollicular interdigitating reticulum cells and more weakly by cells within germinal centres. CD83 is also expressed by Langerhan's cells in the skin. The CD83 antigen is a 186-amino-acid single-chain glycoprotein and this molecule is a member of the immunoglobulin superfamily that is composed of an extracellular V-type Ig-like single domain, a transmembrane region, and a short, 40-amino-acid cytoplasmic tail. CD83 antigen undergoes extensive post-translational glycosylation, since the determined Mr is twice the predicted size of the core protein. However, CD83+ cells have a unique cell surface immuno-phenotype that does not correlate with that of T cells, B cells, NK cells, or cells of the myelomonocytic lineage. CD83+ cells coexpress the highest levels of MHC class II molecules, when compared with other leucocyte lineages. They also co-express T cell markers (CD2, CD5), B cell markers (CD40, CD78), myeloid cell markers (CD13, CD33, CD36), cytokine receptors as well as other cell surface molecules. Diseases associated with CD83 dysfunction include plague and Rift Valley Fever.
同义词
B-cell activation protein; BL11; CD antigen CD83; CD83; CD83 antigen; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 molecule; cell surface protein HB15; cell-surface glycoprotein; HB15; hCD83; mCD83
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