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Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP, AMP, ADP, ATP and UMP are not substrates. Preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP.
1200014F22Rik; 4930513O14Rik; A430102M06Rik; AI414893; ectonucleoside triphosphate diphosphohydrolase 4; ENTPD4; golgi luminal UDPase; guanosine-diphosphatase like protein; KIAA0392; Lalp70; LAP70; Lysal1; lysosomal apyrase-like 1; lysosomal apyrase-like protein of 70 kDa; mKIAA0392; NTPDase 4; NTPDase-4; UDPase; uridine-diphosphatase
100 µg
50 µg
100 µL