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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
2900064I19Rik; AMPA selective glutamate receptor; AMPA-selective glutamate receptor 2; AMPA-selective glutamate receptor 3; dJ1171F9.1; GluA2; GluA3; GLUR2; GluR-2; GLUR3; GluR-3; Gluralpha3; GLURB; gluR-B; GLURC; GLUR-C; GluR-K2; GluR-K3; glutamate ionotropic receptor AMPA type subunit 2; glutamate ionotropic receptor AMPA type subunit 3; glutamate receptor; glutamate receptor 2; Glutamate receptor 3; glutamate receptor B; glutamate receptor B flip isoform; glutamate receptor C; glutamate receptor channel alpha3 subunit; glutamate receptor ionotropic, AMPA 2; Glutamate receptor ionotropic, AMPA 3; glutamate receptor subunit 3; glutamate receptor, ionotrophic, AMPA 3; glutamate receptor, ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA 3; glutamate receptor, ionotropic, AMPA2 (alpha 2); glutamate receptor, ionotropic, AMPA3 (alpha 3); GPRC1C; GRIA2; GRIA3; GRM3; HBGR2; Kiaa4184; MGR3; MRX94
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