Antibodies that detect LIMK2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target LIMK2 in Human, Mouse, Rat and Non-human primate samples. Our LIMK2 polyclonal and...Antibodies that detect LIMK2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target LIMK2 in Human, Mouse, Rat and Non-human primate samples. Our LIMK2 polyclonal and monoclonal antibodies are...Antibodies that detect LIMK2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target LIMK2 in Human, Mouse, Rat and Non-human primate samples. Our LIMK2 polyclonal and monoclonal antibodies are developed in Rabbit, Chicken, Sheep, Mouse and Goat. These antibodies have been verified by Cell treatment to confirm specificity to LIMK2. Find the LIMK2 antibody that fits your needs. Choose from 1 of 31 LIMK2 antibodies, which have been validated in experiments with 24 publications and 51 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with...
Antibodies that detect LIMK2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target LIMK2 in Human, Mouse, Rat and Non-human primate samples. Our LIMK2 polyclonal and monoclonal antibodies are developed in Rabbit, Chicken, Sheep, Mouse and Goat. These antibodies have been verified by Cell treatment to confirm specificity to LIMK2. Find the LIMK2 antibody that fits your needs. Choose from 1 of 31 LIMK2 antibodies, which have been validated in experiments with 24 publications and 51 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
LIMK2 is a serine/threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin. LIMK2 has also been implicated in brain development. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by LIMK2 is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for LIMK2.
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