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Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
AI528662; GAX; Growth arrest-specific homeobox; homeobox protein MOX-2; MEOX2; mesenchyme homeo box 2 (growth arrest-specific homeo box); mesenchyme homeobox 2; Mox2; Mox-2
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