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MTO1 encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene.
2310039H01Rik; 5730419A02Rik; CGI02; CGI-02; COXPD10; homolog of yeast Mto1; LOW QUALITY PROTEIN: protein MTO1 homolog, mitochondrial; mitochondrial MTO1-3; mitochondrial translation optimization 1 homolog; mitochondrial translation optimization 1 homolog (S. cerevisiae); mitochondrial tRNA translation optimization 1; MTO1; Protein MTO1 homolog, mitochondrial
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