NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG. Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.
HGNC:1860; NgR; Ngr1; nogo 66 receptor; Nogo receptor; nogo receptor; Nogo-66 receptor; Nogo66 receptor; nogo-66 receptor; Nogo66 receptor-1; Nogor; OTTHUMP00000197866; reticulon 4 receptor; reticulon-4 receptor; Rtn4r; UNQ330/PRO526
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