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YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.
1190002C07Rik; Adenosine diphosphoribose pyrophosphatase; ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ADP-ribose pyrophosphatase; ADP-ribose pyrophosphatase, mitochondrial; ADP-ribose pyrosphosphatase NUDT9; ADPR-PPase; AI462474; fu33g07; hypothetical protein LOC406661; mitochondrial ADP-ribose pyrophosphatase-like protein; nucleoside diphosphate linked moiety X-type motif 9; nucleoside diphosphate-linked moiety X motif 9; nudix (nucleoside diphosphate linked moiety X)-type motif 9; nudix hydrolase 9; nudix motif 9; nudix -type motif 9; nudix-type motif 9; NUDT10; Nudt9; PSEC0099; sb:cb392; UNQ3012/PRO9771; wu:fj16b09; wu:fu33g07; zgc:63924
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