靶标信息
Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.The B regulatory subunit might modulate substrate selectivity and catalytic activity.
同义词
2410004D02Rik; 2410091N08Rik; 6330556D22Rik; AI790395; alpha isoform of regulatory subunit A, protein phosphatase 2; B55A; B55ALPHA; Medium tumor antigen-associated 61 kDa protein; mKIAA1541; MRD36; PP2A; PP2A subunit A isoform PR65-alpha; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-alpha; PP2A subunit A isoform R1-beta; PP2A subunit B isoform alpha; PP2A subunit B isoform B55-alpha; PP2A subunit B isoform BRA; PP2A subunit B isoform PR55-alpha; PP2A subunit B isoform R2-alpha; PP2A, subunit A, PR65-beta isoform; PP2A, subunit A, R1-beta isoform; PP2A, subunit B, B55-alpha isoform; PP2A, subunit B, B-alpha isoform; PP2A, subunit B, BRA isoform; PP2A, subunit B, PR55-alpha isoform; PP2A, subunit B, R2-alpha isoform; PP2AAALPHA; PP2A-Aalpha; PP2A-Abeta; Ppp2r1a; Ppp2r1b; PPP2R2A; PR52A; PR55A; PR65; PR65A; PR65B; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR52), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform; protein phosphatase 2 regulatory subunit A, alpha; protein phosphatase 2 regulatory subunit A, beta; protein phosphatase 2 regulatory subunit B, alpha; protein phosphatase 2 regulatory subunit Balpha; protein phosphatase 2 scaffold subunit Aalpha; protein phosphatase 2 scaffold subunit Abeta; protein phosphatase 2, regulatory subunit A, alpha; protein phosphatase 2, regulatory subunit A, beta; protein phosphatase 2, regulatory subunit B, alpha; protein phosphatase 2, structural/regulatory subunit A, beta; protein phosphatase PP2A; serine/threonine protein phosphatase 2A, 55 KDA regulatory subunit B, alpha isoform; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform; serine/threonine protein phosphatase A subunit type 2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; testicular secretory protein Li 1; testicular tissue protein Li 156