Antibodies that detect RAD18 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target RAD18 in Human, Rat and Mouse samples. Our RAD18 polyclonal, monoclonal and recombinant...Antibodies that detect RAD18 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target RAD18 in Human, Rat and Mouse samples. Our RAD18 polyclonal, monoclonal and recombinant monoclonal antibodies are...Antibodies that detect RAD18 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target RAD18 in Human, Rat and Mouse samples. Our RAD18 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockdown to confirm specificity to RAD18. Find the RAD18 antibody that fits your needs. Choose from 1 of 23 RAD18 antibodies, which have been validated in experiments with 19 publications and 58 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data...
Antibodies that detect RAD18 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target RAD18 in Human, Rat and Mouse samples. Our RAD18 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Knockdown to confirm specificity to RAD18. Find the RAD18 antibody that fits your needs. Choose from 1 of 23 RAD18 antibodies, which have been validated in experiments with 19 publications and 58 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Human Rad18 (hRad18) is homologue of the S. pombe Rad18 (3,4). In yeast, Rad6 and Rad18 play a crucial role in post-replication repair functions in gap-filling of a daughter strand on replication of damaged DNA (2). Furthermore, Rad6-Rad18 interaction is thought to be critical at an early step during lesion bypass in yeast. In vivo, Rad18 protein forms a tight complex with Rad6 through a conserved ring-finger motif (3,4). It has been suggested that Rad18-Rad6 complex binds to the damaged sites by the single-stranded DNA binding property of Rad 18. This is followed by degradation of the stalled components of DNA replication by ubiquitin-conjugating enzyme activity of Rad6 (1). The human Rad18 maps on chromosome 3p24-25, the region which is often deleted in lung, breast, ovary, and testis cancers. The human RAD18 gene codes for a protein of 495 amino acids with a predicted molecular weight of 56 kDa. The human Rad18 is ubiquitously expressed in various human tissues.
同义词
2810024C04Rik; E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; mRAD18Sc; postreplication repair protein hRAD18p; postreplication repair protein RAD18; post-replication repair protein RAD18SC; Rad18; RAD18 E3 ubiquitin protein ligase; RAD18 homolog; RAD18 homolog (S. cerevisiae); RAD18, E3 ubiquitin protein ligase; RAD18, S. cerevisiae, homolog; Rad18sc; RING finger protein 73; RING-type E3 ubiquitin transferase RAD18; RNF73
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