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The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates.
AA408656; DKFZP586K0919; DKFZp762A152; SENP3; sentrin/SUMO-specific protease 3; sentrin/SUMO-specific protease SENP3; Sentrin-specific protease 3; Smt3ip; Smt3ip1; Smt3-specific isopeptidase 1; SSP3; SUMO specific peptidase 3; SUMO/sentrin specific peptidase 3; SUMO/sentrin specific protease 3; SUMO1/sentrin/SMT3 specific peptidase 3; SUMO1/sentrin/SMT3 specific protease 3; SUMO-1-specific protease 3; SUSP3; Ulp1
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