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TUP 1 and SSN6 are involved in repression of several diverse families of genes in yeast, including cell type-specific genes regulated by the alphga2 and a1/alpha2 repressors. Ssn6-Tupl interacts with class I histone deacetylases required for repression, and rfecrfuitment of yeast Tuplp-Ssn6p repressor is associated with localized decreases in histone acetylation.
AAR1; AER2; AMM1; chromatin-silencing transcriptional regulator TUP1; CRT4; CYC9; FLK1; Flocculation suppressor protein; General transcriptional corepressor TUP1; Glucose repression regulatory protein TUP1; Repressor AER2; ROX4; SFL2; TUP1; UMR7; YCR084C; YCR84C
100 µg