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Lymphotactin, otherwise known as XCL1, is a member of the C-chemokine family that uniquely acts as a chemoattractant for lymphocytes, but not monocytes or neutrophils, suggesting an important regulatory role in lymphocyte trafficking and inflammation. Lymphotactin, shown to signal through chemokine XC receptor 1 (XCR1), is detected at the highest level in the spleen and at low levels in the lungs, small intestine and colon, and is abundantly and selectively expressed by activated T cells, in particular CD8+ T cells, and is also produced by NK cells.
AI661682; ATAC; C motif chemokine 1; c motif chemokine 2; chemokine (C motif) ligand 1; chemokine (C motif) ligand 2; cytokine SCM-1; Cytokine SCM-1 beta; Lptn; LTN; Lymphotactin; lymphotaxin; SCM1; SCM-1; SCM1A; SCM-1a; SCM-1-alpha; SCM1B; SCM-1b; Scyc1; SCYC2; single cysteine motif 1a; small inducible cytokine subfamily C, member 1 (lymphotactin); small inducible cytokine subfamily C, member 2; small-inducible cytokine C1; XC chemokine ligand 1; XC chemokine ligand 2; X-C motif chemokine ligand 1; X-C motif chemokine ligand 2; Xcl1; XCL2
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