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ZBTB1 acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis. Plays a key role in the transcriptional regulation of T lymphocyte development.
9430077A12; AI256369; brain specific protein 2; Bsg2; C430003J21Rik; KIAA0997; Zbtb1; zinc finger and BTB domain containing 1; zinc finger and BTB domain-containing protein 1; ZNF909
100 µg
100 µL
100 µL
100 µL
10 µL