Product References
Indole-3-pyruvic acid alleviates rheumatoid arthritis via the aryl hydrocarbon receptor pathway.
Annals of translational medicine
Huang T,Cheng L,Jiang Y,Zhang L,Qian L
12-7179-42 was used in Flow Cytometry to reveal the effect and mechanism of indole-3-pyruvic acid (IPA) in rheumatoid arthritis (RA).
Wed Mar 15 00:00:00 EDT 2023
Cathepsin S inhibition in dendritic cells prevents Th17 cell differentiation in perivascular adipose tissues following vascular injury in diabetic rats.
Journal of biochemical and molecular toxicology
Peng H,Lv Y,Li C,Cheng Z,He S,Wang C,Liu J
12-7179-42 was used in Flow Cytometry to investigate the role of CTSS in restenosis following carotid injury in diabetic rats.
Fri Sep 01 00:00:00 EDT 2023
EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis.
Arthritis research & therapy
Park JS,Yang SC,Jeong HY,Lee SY,Ryu JG,Choi JW,Kang HY,Kim SM,Hwang SH,Cho ML,Park SH
12-7179-42 was used in Flow cytometry/Cell sorting to investigate the efficacy of EC-18 on the development of RA.
Thu Nov 17 00:00:00 EST 2022
CD4+ T cells persist for years in the human small intestine and display a TH1 cytokine profile.
Mucosal immunology
Bartolomé-Casado R,Landsverk OJB,Chauhan SK,Sætre F,Hagen KT,Yaqub S,Øyen O,Horneland R,Aandahl EM,Aabakken L,Bækkevold ES,Jahnsen FL
12-7179-42 was used in Flow Cytometry to show that the intestinal CD4+ T-cell compartment is dominated by resident populations that survive for more than 1 year.
Mon Mar 01 00:00:00 EST 2021
Dysregulated Peripheral Invariant Natural Killer T Cells in Plaque Psoriasis Patients.
Frontiers in cell and developmental biology
Hu Y,Chen Y,Chen Z,Zhang X,Guo C,Yu Z,Xu P,Sun L,Zhou X,Gong Y,Yu Q,Shi Y
12-7179-42 was used in Flow cytometry/Cell sorting to explore the expression of iNKT cells in psoriasis patients and the effect of secukinumab on them.
Wed Feb 23 00:00:00 EST 2022
Immunomodulatory Effects of Canine Adipose Tissue Mesenchymal Stem Cell-Derived Extracellular Vesicles on Stimulated CD4+ T Cells Isolated from Peripheral Blood Mononuclear Cells.
Journal of immunology research
Teshima T,Yuchi Y,Suzuki R,Matsumoto H,Koyama H
12-7179-42 was used in Flow cytometry/Cell sorting to investigate the the immunomodulatory effects of canine Adipose tissue-derived mesenchymal stem cells on immune cells - derived extracellular vesicles.
Mon Jan 24 00:00:00 EST 2022
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation.
Nature communications
Minns D,Smith KJ,Alessandrini V,Hardisty G,Melrose L,Jackson-Jones L,MacDonald AS,Davidson DJ,Gwyer Findlay E
12-7179-42 was used in Flow cytometry/Cell sorting to investigate if cathelicidin is a powerful Th17 potentiator which enhances aryl hydrocarbon receptor (AHR) and RORγt expression, in a TGF-β1-dependent manner.
Wed Feb 24 00:00:00 EST 2021
Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis.
Journal of neuroinflammation
Chen YH,Eskandarpour M,Zhang X,Galatowicz G,Greenwood J,Lightman S,Calder V
12-7179-42 was used in Flow Cytometry to show that the α4β1 integrin inhibitor may exert a modulatory effect in EAU progression by selectively blocking Th17 cell migration across the blood-retinal barrier without affecting systemic CD4+ T cell subsets.
Thu Feb 18 00:00:00 EST 2021
Immune-checkpoint blockade of CTLA-4 (CD152) in antigen-specific human T-cell responses differs profoundly between neonates, children, and adults.
Oncoimmunology
Arra A,Pech M,Fu H,Lingel H,Braun F,Beyer C,Spiliopoulou M,Bröker BM,Lampe K,Arens C,Vogel K,Pierau M,Brunner-Weinzierl MC
12-7179-42 was used in Flow Cytometry to show that T-cell proliferation as well as frequencies of antigen-specific T-cells (CD40L+CD4+) were enhanced in neonatal T-cells upon CTLA-4 blockade.
Mon Jun 14 00:00:00 EDT 2021
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease.
Cell
Lee JY,Hall JA,Kroehling L,Wu L,Najar T,Nguyen HH,Lin WY,Yeung ST,Silva HM,Li D,Hine A,Loke P,Hudesman D,Martin JC,Kenigsberg E,Merad M,Khanna KM,Littman DR
12-7179 was used in Flow cytometry/Cell sorting to suggest that serum amyloid A proteins direct a pathogenic pro-inflammatory Th17 cell differentiation program and promote Th17-mediated inflammatory diseases.
Thu Jan 09 00:00:00 EST 2020
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.
Cell
Sekine T,Perez-Potti A,Rivera-Ballesteros O,Strålin K,Gorin JB,Olsson A,Llewellyn-Lacey S,Kamal H,Bogdanovic G,Muschiol S,Wullimann DJ,Kammann T,Emgård J,Parrot T,Folkesson E,Rooyackers O,Eriksson LI,Henter JI,Sönnerborg A,Allander T,Albert J,Nielsen M,Klingström J,Gredmark-Russ S,Björkström NK,Sandberg JK,Price DA,Ljunggren HG,Aleman S,Buggert M
12-7179 was used in Flow cytometry/Cell sorting to systematically mapp the functional and phenotypic landscape of SARS-CoV-2-specific T cell responses in unexposed individuals, exposed family members, and individuals with acute or convalescent COVID-19.
Thu Oct 01 00:00:00 EDT 2020
Th17/Treg imbalance modulates rat myocardial fibrosis and heart failure by regulating LOX expression.
Acta physiologica (Oxford, England)
Lu M,Qin X,Yao J,Yang Y,Zhao M,Sun L
12-7179-42 was used in Flow cytometry/Cell sorting to decipher the regulatory mechanism of Th17/Treg on LOX expression and to validate whether Th17/Treg imbalance regulates myocardial fibrosis by modulating LOX expression.
Sun Nov 01 00:00:00 EDT 2020
Differential influences of the BPA, BPS and BPF on in vitro IL-17 secretion by mouse and human T cells.
Toxicology in vitro : an international journal published in association with BIBRA
Malaisé Y,Le Mentec H,Sparfel L,Guzylack-Piriou L
12-7179-42 was used in Flow Cytometry to analyse the effects of bisphenols on Th17 properties and function.
Tue Dec 01 00:00:00 EST 2020
IL-12-Induced Immune Suppressive Deficit During CD8+ T-Cell Differentiation.
Frontiers in immunology
Renavikar PS,Sinha S,Brate AA,Borcherding N,Crawford MP,Steward-Tharp SM,Karandikar NJ
12-7179 was used in Flow cytometry/Cell sorting to provide insights into the role of T-cell differentiation in CD8 suppressive biology and may reveal therapeutically targetable pathways to reverse suppressive deficit during immune-mediated disease.
Thu May 13 00:00:00 EDT 2021
Paradoxical psoriasis induced by TNF-α blockade shows immunological features typical of the early phase of psoriasis development.
The journal of pathology. Clinical research
Fania L,Morelli M,Scarponi C,Mercurio L,Scopelliti F,Cattani C,Scaglione GL,Tonanzi T,Pilla MA,Pagnanelli G,Mazzanti C,Girolomoni G,Cavani A,Madonna S,Albanesi C
12-7179 was used in Flow cytometry/Cell sorting to investigate the immunological and genetic profiles of hidradenitis suppurativa patients without psoriasis who developed paradoxical psoriasiform reactions following anti-TNF-α therapy with adalimumab.
Wed Jan 01 00:00:00 EST 2020
In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists.
International journal of molecular sciences
Gramlich R,Aliahmadi E,Peiser M
12-7179-42 was used in Flow Cytometry to investigate combinatory effects on Th cell polarization by bacterial cell wall compounds peptidoglycan (PGN) and lipopolysaccharide (LPS) and by bacterial nucleic acid (DNA).
Tue Mar 19 00:00:00 EDT 2019
The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling.
Cell metabolism
Ricciardi S,Manfrini N,Alfieri R,Calamita P,Crosti MC,Gallo S,Müller R,Pagani M,Abrignani S,Biffo S
12-7179 was used in Flow cytometry/Cell sorting to discover that T cells fulfill this transitional process through translational control.
Tue Dec 04 00:00:00 EST 2018
The NRF2 pathway as potential biomarker for dimethyl fumarate treatment in multiple sclerosis.
Annals of clinical and translational neurology
Hammer A,Waschbisch A,Kuhbandner K,Bayas A,Lee DH,Duscha A,Haghikia A,Gold R,Linker RA
12-7179 was used in Flow cytometry/Cell sorting to demonstrate that positive effects of DMF on the clinical outcome are paralleled by induction of the antioxidant NRF2 transcriptional pathway and a shift toward regulatory immune cell subsets in the periphery.
Fri Jun 01 00:00:00 EDT 2018
CD39+ regulatory T cells accumulate in colon adenocarcinomas and display markers of increased suppressive function.
Oncotarget
Ahlmanner F,Sundström P,Akeus P,Eklöf J,Börjesson L,Gustavsson B,Lindskog EB,Raghavan S,Quiding-Järbrink M
12-7179 was used in Flow cytometry/Cell sorting to treg therapy may hamper development of long-term tolerance and should be approached with caution in the clinical autologous setting.
Tue Dec 11 00:00:00 EST 2018
The transcription factor CREM drives an inflammatory phenotype of T cells in oligoarticular juvenile idiopathic arthritis.
Pediatric rheumatology online journal
Ohl K,Nickel H,Moncrieffe H,Klemm P,Scheufen A,Föll D,Wixler V,Schippers A,Wagner N,Wedderburn LR,Tenbrock K
12-7179 was used in Flow cytometry/Cell sorting to study the role of the cAMP response element α in regulation of effector T cells within the inflammatory joint.
Wed Jun 20 00:00:00 EDT 2018
IL-2 Inhibition of Th17 Generation Rather Than Induction of Treg Cells Is Impaired in Primary Sjögren's Syndrome Patients.
Frontiers in immunology
Luo J,Ming B,Zhang C,Deng X,Li P,Wei Z,Xia Y,Jiang K,Ye H,Ma W,Liu Z,Li H,Yang XP,Dong L
Mon Sep 16 00:00:00 EDT 2019
Effect of Equipotent Doses of Propofol versus Sevoflurane Anesthesia on Regulatory T Cells after Breast Cancer Surgery.
Anesthesiology
Oh CS,Lee J,Yoon TG,Seo EH,Park HJ,Piao L,Lee SH,Kim SH
12-7179-42 was used in Flow cytometry/Cell sorting to show that changes in immune cells were similar with propofol and sevoflurane during breast cancer surgery.
Thu Nov 01 00:00:00 EDT 2018
Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease.
Nature medicine
West NR,Hegazy AN,Owens BMJ,Bullers SJ,Linggi B,Buonocore S,Coccia M,Görtz D,This S,Stockenhuber K,Pott J,Friedrich M,Ryzhakov G,Baribaud F,Brodmerkel C,Cieluch C,Rahman N,Müller-Newen G,Owens RJ,Kühl AA,Maloy KJ,Plevy SE,Keshav S,Travis SPL,Powrie F
12-7179 was used in Flow cytometry/Cell sorting to study how cytokine oncostatin M is a potential biomarker and therapeutic target for IBD, and has particular relevance for anti-TNF-resistant patients.
Mon May 01 00:00:00 EDT 2017
Age-associated alteration in Th17 cell response is related to endothelial cell senescence and atherosclerotic cerebral infarction.
American journal of translational research
Li Q,Ding S,Wang YM,Xu X,Shen Z,Fu R,Liu M,Hu C,Zhang C,Cao Q,Wang Y
Thu Oct 01 00:00:00 EDT 2020
IL-1β induced HIF-1α inhibits the differentiation of human FOXP3+ T cells.
Scientific reports
Feldhoff LM,Rueda CM,Moreno-Fernandez ME,Sauer J,Jackson CM,Chougnet CA,Rupp J
12-7179 was used in Flow cytometry/Cell sorting to investigate the effects exerted by inflammation on human iTreg differentiation.
Tue Mar 28 00:00:00 EDT 2017
Protective effect of 1α,25-dihydroxyvitamin D3 on effector CD4+ T cell induced injury in human renal proximal tubular epithelial cells.
PloS one
Chung BH,Kim BM,Doh KC,Cho ML,Kim KW,Yang CW
12-7179 was used in Flow cytometry/Cell sorting to suggest that vitamin D may have a significant role in the regulation of inflammation in allograft tissue in kidney transplant recipients.
Mon Aug 28 00:00:00 EDT 2017
Cytochrome P450s in human immune cells regulate IL-22 and c-Kit via an AHR feedback loop.
Scientific reports
Effner R,Hiller J,Eyerich S,Traidl-Hoffmann C,Brockow K,Triggiani M,Behrendt H,Schmidt-Weber CB,Buters JT
12-7179 was used in Flow cytometry/Cell sorting to study the interdependence of Cytochrome P4501 enzymes and aryl hydrocarbon receptor in human primary immune cells.
Thu Mar 09 00:00:00 EST 2017
Impact of immunosuppressive drugs on the therapeutic efficacy of ex vivo expanded human regulatory T cells.
Haematologica
Scottà C,Fanelli G,Hoong SJ,Romano M,Lamperti EN,Sukthankar M,Guggino G,Fazekasova H,Ratnasothy K,Becker PD,Afzali B,Lechler RI,Lombardi G
12-7179 was used in Flow cytometry/Cell sorting to study the effect of immunosuppressive drugs on Treg cells.
Fri Jan 01 00:00:00 EST 2016
Booster vaccination against tetanus and diphtheria: insufficient protection against diphtheria in young and elderly adults.
Immunity & ageing : I & A
Grasse M,Meryk A,Schirmer M,Grubeck-Loebenstein B,Weinberger B
12-7179 was used in Flow cytometry/Cell sorting to highlight that booster vaccines against tetanus and diphtheria only provide long-lasting protection against tetanus and not diphtheria, independently of age.
Wed Sep 07 00:00:00 EDT 2016
TGF-β Affects the Differentiation of Human GM-CSF+ CD4+ T Cells in an Activation- and Sodium-Dependent Manner.
Frontiers in immunology
Éliás S,Schmidt A,Kannan V,Andersson J,Tegnér J
12-7179 was used in Flow cytometry/Cell sorting to study the environmental cues that promote differentiation of granulocyte-macrophage colony-stimulating factor producing T cells.
Wed Nov 20 00:00:00 EST 2019
CCR6(-) regulatory T cells blunt the restoration of gut Th17 cells along the CCR6-CCL20 axis in treated HIV-1-infected individuals.
Mucosal immunology
Loiseau C,Requena M,Mavigner M,Cazabat M,Carrere N,Suc B,Barange K,Alric L,Marchou B,Massip P,Izopet J,Delobel P
12-7179 was used in Flow cytometry/Cell sorting to study effect of HIV-1 infection on the CCR6-CCL20 chemotactic axis in small intestine epithelial cells.
Thu Sep 01 00:00:00 EDT 2016
IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation, and microbiome in ARV-treated, SIV-infected macaques.
Mucosal immunology
Ortiz AM,Klase ZA,DiNapoli SR,Vujkovic-Cvijin I,Carmack K,Perkins MR,Calantone N,Vinton CL,Riddick NE,Gallagher J,Klatt NR,McCune JM,Estes JD,Paiardini M,Brenchley JM
12-7179 was used in Flow cytometry/Cell sorting to investigate methods to promote Th17 cell recovery in individuals infected with HIV, showing that IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation, and microbiome in antiretroviral-treated, SIV-infected macaques.
Tue Mar 01 00:00:00 EST 2016
Vaccination against canine leishmaniosis increases the phagocytic activity, nitric oxide production and expression of cell activation/migration molecules in neutrophils and monocytes.
Veterinary parasitology
Moreira ML,Costa-Pereira C,Alves ML,Marteleto BH,Ribeiro VM,Peruhype-Magalhães V,Giunchetti RC,Martins-Filho OA,Araújo MS
12717942 was used in flow cytometry to assess the protective immunological events induced by vaccination with Leishmune in dogs
Fri Apr 15 00:00:00 EDT 2016
FOXP3+ associated with the pro-inflammatory regulatory T and T helper 17 effector cells in asthma patients.
Experimental and therapeutic medicine
Zhang JG,Chen XJ,Liu T,Jiang SJ
12-7179 was used in Flow cytometry/Cell sorting to evaluate whether peripheral blood samples from asthma patients contain reduced Treg cells and increased Th17 cells.
Sat Oct 01 00:00:00 EDT 2016
IL-17A- and IFNγ-Producing T Cells in Healthy Skin.
Scandinavian journal of immunology
Dyring-Andersen B,Nielsen MM,Geisler C,Bonefeld CM,Skov L
12-7179-42 was used in Flow cytometry/Cell sorting to discuss IL-17a and IFNy producing T cells in healthy skin.
Fri Apr 01 00:00:00 EDT 2016
ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation.
eLife
Pearson C,Thornton EE,McKenzie B,Schaupp AL,Huskens N,Griseri T,West N,Tung S,Seddon BP,Uhlig HH,Powrie F
12-7179 was used in Flow cytometry/Cell sorting to investigate how a small population of innate lymphoid cells (ILCs) has large effects on immune homeostasis, showing that ILC3s produce GM-CSF to orchestrate acute intestinal inflammation.
Mon Jan 18 00:00:00 EST 2016
Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire.
Proceedings of the National Academy of Sciences of the United States of America
Dimova T,Brouwer M,Gosselin F,Tassignon J,Leo O,Donner C,Marchant A,Vermijlen D
12-7179 was used in Flow cytometry/Cell sorting to study the T-cell receptor which contains the γ-chain variable region 9 and the δ-chain variable region 2s in the the human fetal γδ T-cell repertoire.
Tue Feb 10 00:00:00 EST 2015
NY-ESO-1 specific antibody and cellular responses in melanoma patients primed with NY-ESO-1 protein in ISCOMATRIX and boosted with recombinant NY-ESO-1 fowlpox virus.
International journal of cancer
Chen JL,Dawoodji A,Tarlton A,Gnjatic S,Tajar A,Karydis I,Browning J,Pratap S,Verfaille C,Venhaus RR,Pan L,Altman DG,Cebon JS,Old LL,Nathan P,Ottensmeier C,Middleton M,Cerundolo V
12-7179 was used in Immunocytochemistry-immunoflourescence to examine whether heterologous prime-boost strategies based on the combination with NY-ESO-1 ISCOMATRIX with different NY-ESO-1 boosting reagents could increase NY-ESO-1 CD8(+) or CD4(+) T cell responses.
Sun Mar 15 00:00:00 EDT 2015
Human Mucosa-Associated Invariant T Cells Accumulate in Colon Adenocarcinomas but Produce Reduced Amounts of IFN-γ.
Journal of immunology (Baltimore, Md. : 1950)
Sundström P,Ahlmanner F,Akéus P,Sundquist M,Alsén S,Yrlid U,Börjesson L,Sjöling Å,Gustavsson B,Wong SB,Quiding-Järbrink M
12-7179 was used in Flow cytometry/Cell sorting to elucidate the presence and function of mucosa-associated invariant T cells in tumours.
Thu Oct 01 00:00:00 EDT 2015
DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.
Human molecular genetics
Volk T,Pannicke U,Reisli I,Bulashevska A,Ritter J,Björkman A,Schäffer AA,Fliegauf M,Sayar EH,Salzer U,Fisch P,Pfeifer D,Di Virgilio M,Cao H,Yang F,Zimmermann K,Keles S,Caliskaner Z,Güner SÜ,Schindler D,Hammarström L,Rizzi M,Hummel M,Pan-Hammarström Q,Schwarz K,Grimbacher B
12-7179 was used in Flow cytometry/Cell sorting to investigate the range of phenotypes associated with DCLRE1C (ARTEMIS) mutations in humans.
Sun Dec 20 00:00:00 EST 2015
Cross-reactivity of commercially available anti-human monoclonal antibodies with canine cytokines: establishment of a reliable panel to detect the functional profile of peripheral blood lymphocytes by intracytoplasmic staining.
Acta veterinaria Scandinavica
Moreira ML,Dorneles EM,Soares RP,Magalhães CP,Costa-Pereira C,Lage AP,Teixeira-Carvalho A,Martins-Filho OA,Araújo MS
12-7179 was used in Flow cytometry/Cell sorting to screen a panel of 17 monoclonal antibodies against human cytokines for cross-reactivity against canine cytokines.
Fri Sep 11 00:00:00 EDT 2015
Cross-reactivity of commercially available anti-human monoclonal antibodies with canine cytokines: establishment of a reliable panel to detect the functional profile of peripheral blood lymphocytes by intracytoplasmic staining.
Acta veterinaria Scandinavica
Moreira ML,Dorneles EM,Soares RP,Magalhães CP,Costa-Pereira C,Lage AP,Teixeira-Carvalho A,Martins-Filho OA,Araújo MS
12-7179 was used in Flow cytometry/Cell sorting to screen a panel of 17 monoclonal antibodies against human cytokines for cross-reactivity against canine cytokines.
Fri Sep 11 00:00:00 EDT 2015
Increase of Th17 Cell Phenotype in Kidney Transplant Recipients with Chronic Allograft Dysfunction.
PloS one
Chung BH,Kim KW,Kim BM,Doh KC,Cho ML,Yang CW
12-7179 was used in Flow cytometry/Cell sorting to determine the association of Th17 cell phenotype with chronic allograft dysfunction, showing an increase in Th17 phenotype in kidney transplant recipients with allograft dysfunction.
Mon Jun 27 00:00:00 EDT 2016
Optimization of adipose tissue-derived mesenchymal stem cells by rapamycin in a murine model of acute graft-versus-host disease.
Stem cell research & therapy
Kim KW,Moon SJ,Park MJ,Kim BM,Kim EK,Lee SH,Lee EJ,Chung BH,Yang CW,Cho ML
12-7179 was used in Flow cytometry/Cell sorting to optimize the functional properties of MSCs to increase the protection for bone marrow transplantation recipients from the lethal acute graft-versus-host disease development.
Fri Oct 23 00:00:00 EDT 2015
Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach.
Retrovirology
Cleret-Buhot A,Zhang Y,Planas D,Goulet JP,Monteiro P,Gosselin A,Wacleche VS,Tremblay CL,Jenabian MA,Routy JP,El-Far M,Chomont N,Haddad EK,Sekaly RP,Ancuta P
12-7179 was used in Flow cytometry/Cell sorting to investigate molecular mechanisms of HIV permissiveness in Th17 cells, revealing novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells.
Thu Dec 10 00:00:00 EST 2015
Agonistic induction of PPARγ reverses cigarette smoke-induced emphysema.
The Journal of clinical investigation
Shan M,You R,Yuan X,Frazier MV,Porter P,Seryshev A,Hong JS,Song LZ,Zhang Y,Hilsenbeck S,Whitehead L,Zarinkamar N,Perusich S,Corry DB,Kheradmand F
12-7179 was used in Flow cytometry/Cell sorting to reveal a proinflammatory pathway, in which reduced PPARγ activity promotes emphysema.
Sat Mar 01 00:00:00 EST 2014
The disturbance of TH17-Treg cell balance in adenomyosis.
Fertility and sterility
Gui T,Chen C,Zhang Z,Tang W,Qian R,Ma X,Cao P,Wan G
12-7179 was used in Flow cytometry/Cell sorting to investigate the balance between Treg and T(H)17 cells in peripheral blood and uteri of women with adenomyosis.
Sat Feb 01 00:00:00 EST 2014
Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration.
PLoS pathogens
Sereti I,Estes JD,Thompson WL,Morcock DR,Fischl MA,Croughs T,Beq S,Lafaye de Micheaux S,Yao MD,Ober A,Wilson EM,Natarajan V,Imamichi H,Boulassel MR,Lederman MM,Routy JP
12-7179 was used in Flow cytometry/Cell sorting to test the efficacy of IL-7 adjunctive therapy on T-cell reconstitution in antiretroviral therapy-suppressed HIV patients.
Wed Jan 01 00:00:00 EST 2014
Patients with the most advanced rheumatoid arthritis remain with Th1 systemic defects after TNF inhibitors treatment despite clinical improvement.
Rheumatology international
Kosmaczewska A,Swierkot J,Ciszak L,Szteblich A,Chrobak A,Karabon L,Partyka A,Szechinski J,Wiland P,Frydecka I
12-7179 was used in Flow cytometry/Cell sorting to demonstrate that both the extent of systemic immune abnormalities and their restoration are dependent on duration of the active RA.
Sat Feb 01 00:00:00 EST 2014
Whole CMV proteome pattern recognition analysis after HSCT identifies unique epitope targets associated with the CMV status.
PloS one
Pérez-Bercoff L,Valentini D,Gaseitsiwe S,Mahdavifar S,Schutkowski M,Poiret T,Pérez-Bercoff Å,Ljungman P,Maeurer MJ
12-7179 was used in Flow cytometry/Cell sorting to screen the entire CMV proteome to visualise the humoral target epitope-focus profile in serum after haematopoietic stem cell transplantation.
Wed Jan 14 00:00:00 EST 2015
Immunomodulation of human intestinal T cells by the synthetic CD80 antagonist RhuDex®.
Immunity, inflammation and disease
Heninger AK,Wentrup S,Al-Saeedi M,Schiessling S,Giese T,Wartha F,Meuer S,Schröder-Braunstein J
12-7179 was used in Flow cytometry/Cell sorting to show how a synthetic CD80 antagonist can be used to modulate the human intestinal T cell response.
Sat Nov 01 00:00:00 EDT 2014
Induction and stability of human Th17 cells require endogenous NOS2 and cGMP-dependent NO signaling.
The Journal of experimental medicine
Obermajer N,Wong JL,Edwards RP,Chen K,Scott M,Khader S,Kolls JK,Odunsi K,Billiar TR,Kalinski P
12-7179 was used in Flow cytometry/Cell sorting to indicate that NO is critically required for the induction and stability of human Th17 responses.
Mon Jul 01 00:00:00 EDT 2013
Patients with cystic fibrosis have inducible IL-17+IL-22+ memory cells in lung draining lymph nodes.
The Journal of allergy and clinical immunology
Chan YR,Chen K,Duncan SR,Lathrop KL,Latoche JD,Logar AJ,Pociask DA,Wahlberg BJ,Ray P,Ray A,Pilewski JM,Kolls JK
12-7179 was used in Flow cytometry/Cell sorting to determine the frequency of TH17 cells in cystic fibrosis patients.
Mon Apr 01 00:00:00 EDT 2013
Association of a NOD2 gene polymorphism and T-helper 17 cells with presumed ocular toxoplasmosis.
The Journal of infectious diseases
Dutra MS,Béla SR,Peixoto-Rangel AL,Fakiola M,Cruz AG,Gazzinelli A,Quites HF,Bahia-Oliveira LM,Peixe RG,Campos WR,Higino-Rocha AC,Miller NE,Blackwell JM,Antonelli LR,Gazzinelli RT
12-7179 was used in Flow cytometry/Cell sorting to suggest that NOD2 influences the production of IL-17A by CD4 T lymphocytes and might contribute to the development of ocular toxoplasmosis.
Tue Jan 01 00:00:00 EST 2013
Peripheral Th17/Treg imbalance in patients with atherosclerotic cerebral infarction.
International journal of clinical and experimental pathology
Li Q,Wang Y,Yu F,Wang YM,Zhang C,Hu C,Wu Z,Xu X,Hu S
12-7179 was used in Flow cytometry/Cell sorting to study how Th17/Treg cells were imbalanced in ACI patients, and ox-LDL may contribute to this imbalance and lead to the occurrence of ACI.
Mon Dec 23 00:00:00 EST 2013
Elevated frequencies of circulating Th22 cell in addition to Th17 cell and Th17/Th1 cell in patients with acute coronary syndrome.
PloS one
Zhang L,Wang T,Wang XQ,Du RZ,Zhang KN,Liu XG,Ma DX,Yu S,Su GH,Li ZH,Guan YQ,Du NL
12-7179 was used in Flow cytometry/Cell sorting to investigate the roles and profiles of T helper cells in the pathogenesis of inflammatory heart diseases.
Mon Aug 18 00:00:00 EDT 2014
Cigarette smoke induction of osteopontin (SPP1) mediates T(H)17 inflammation in human and experimental emphysema.
Science translational medicine
Shan M,Yuan X,Song LZ,Roberts L,Zarinkamar N,Seryshev A,Zhang Y,Hilsenbeck S,Chang SH,Dong C,Corry DB,Kheradmand F
12-7179 was used in Flow cytometry/Cell sorting to show that cigarette smoke increases the expression of IL-17A in both CD4+ and γδ T cells from mouse lung.
Wed Jan 18 00:00:00 EST 2012
Characterization of Th17 responses to Streptococcus pneumoniae in humans: comparisons between adults and children in a developed and a developing country.
Vaccine
Lundgren A,Bhuiyan TR,Novak D,Kaim J,Reske A,Lu YJ,Qadri F,Malley R
12-7179 was used in Flow cytometry/Cell sorting to compare different Th17 responses to pneumococcal antigens and whole cell antigens, in children and adults in both developed and developing countries.
Wed Jun 06 00:00:00 EDT 2012
The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid.
PloS one
Wacleche VS,Chomont N,Gosselin A,Monteiro P,Goupil M,Kared H,Tremblay C,Bernard N,Boulassel MR,Routy JP,Ancuta P
12-7179 was used in Flow cytometry/Cell sorting to investigate the colocalisation potential of HIV-specific CD8(+) and CD4(+) T-cells into gut-associated lymphoid tissues.
Fri Aug 03 00:00:00 EDT 2012
Frequency of Th17 CD4+ T cells in early rheumatoid arthritis: a marker of anti-CCP seropositivity.
PloS one
Arroyo-Villa I,Bautista-Caro MB,Balsa A,Aguado-Acín P,Nuño L,Bonilla-Hernán MG,Puig-Kröger A,Martín-Mola E,Miranda-Carús ME
12-7179 was used in Flow cytometry/Cell sorting to examine the frequency and phenotype of Th17 cells in the peripheral blood of early rheumatoid arthritis patients.
Tue Feb 19 00:00:00 EST 2013
Dysregulation of Th17 cells during the early post-transplant period in patients under calcineurin inhibitor based immunosuppression.
PloS one
Chung BH,Kim KW,Kim BM,Piao SG,Lim SW,Choi BS,Park CW,Kim YS,Cho ML,Yang CW
12-7179 was used in Flow cytometry/Cell sorting to investigate changes in the immune cell subsets of renal transplant recipients before transplant and during the early posttransplant period.
Thu Jan 10 00:00:00 EST 2013
Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7.
Journal of immunology (Baltimore, Md. : 1950)
Monteiro P,Gosselin A,Wacleche VS,El-Far M,Said EA,Kared H,Grandvaux N,Boulassel MR,Routy JP,Ancuta P
12-7179 was used in Immunocytochemistry to show that, regardless of their integrin expression, productive HIV type 1 infection preferentially targets memory CCR6+CD4+ T cells.
Fri Apr 15 00:00:00 EDT 2011
Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7.
Journal of immunology (Baltimore, Md. : 1950)
Monteiro P,Gosselin A,Wacleche VS,El-Far M,Said EA,Kared H,Grandvaux N,Boulassel MR,Routy JP,Ancuta P
12-7179 was used in Immunocytochemistry to show that, regardless of their integrin expression, productive HIV type 1 infection preferentially targets memory CCR6+CD4+ T cells.
Fri Apr 15 00:00:00 EDT 2011
IL-1β and TGF-β act antagonistically in induction and differentially in propagation of human proinflammatory precursor CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Hebel K,Rudolph M,Kosak B,Chang HD,Butzmann J,Brunner-Weinzierl MC
12-7179 was used in Flow cytometry/Cell sorting to monitor early T cell differentiation after T cell activation in the presence of different inflammatory cytokines.
Thu Dec 01 00:00:00 EST 2011
Complement component C5a promotes expression of IL-22 and IL-17 from human T cells and its implication in age-related macular degeneration.
Journal of translational medicine
Liu B,Wei L,Meyerle C,Tuo J,Sen HN,Li Z,Chakrabarty S,Agron E,Chan CC,Klein ML,Chew E,Ferris F,Nussenblatt RB
12-7179 was used in Flow cytometry/Cell sorting to show that the possible involvement of IL-22 and IL-17 in the inflammation that contributes to AMD may herald a new treatment approach.
Fri Jul 15 00:00:00 EDT 2011
Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950)
Gosselin A,Monteiro P,Chomont N,Diaz-Griffero F,Said EA,Fonseca S,Wacleche V,El-Far M,Boulassel MR,Routy JP,Sekaly RP,Ancuta P
12-7179 was used in Flow cytometry/Cell sorting to establish a link between HIV permissiveness, phenotype/homing potential, and lineage commitment in primary CD4(+) T cells.
Mon Feb 01 00:00:00 EST 2010
Human plasmacytoid dendritic cells support Th17 cell effector function in response to TLR7 ligation.
Journal of immunology (Baltimore, Md. : 1950)
Yu CF,Peng WM,Oldenburg J,Hoch J,Bieber T,Limmer A,Hartmann G,Barchet W,Eis-Hübinger AM,Novak N
12-7179 was used in Flow cytometry/Cell sorting to demonstrate that plasmacytoid dendritic cells are capable of promoting Th17 differentiation in response to TLR7 stimulation.
Mon Feb 01 00:00:00 EST 2010
Generation of IL-23 producing dendritic cells (DCs) by airborne fungi regulates fungal pathogenicity via the induction of T(H)-17 responses.
PloS one
Chamilos G,Ganguly D,Lande R,Gregorio J,Meller S,Goldman WE,Gilliet M,Kontoyiannis DP
12-7179 was used in Flow cytometry/Cell sorting to demonstrate how opportunistic fungal pathogens trigger a common innate sensing pathway in human dendritic cells that results in robust Interleukin-23 production and drives T helper cells 17 responses.
Thu Sep 23 00:00:00 EDT 2010
Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing.
Clinical cancer research : an official journal of the American Association for Cancer Research
Sfanos KS,Bruno TC,Maris CH,Xu L,Thoburn CJ,DeMarzo AM,Meeker AK,Isaacs WB,Drake CG
12-7179 was used in Flow cytometry/Cell sorting to reveal a potential role for TH17 and regulatory CD4+ T cells in the development or progression of prostate cancer.
Sun Jun 01 00:00:00 EDT 2008
Prolonged, granulocyte-macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha.
Arthritis research & therapy
Parsonage G,Filer A,Bik M,Hardie D,Lax S,Howlett K,Church LD,Raza K,Wong SH,Trebilcock E,Scheel-Toellner D,Salmon M,Lord JM,Buckley CD
12-7179 was used in Immunofluorescence to study the increased number of neutrophils with extended lifespan following fibroblast activation by IL-17 and TNFalpha in the rheumatoid synovial microenvironment.
Tue Sep 23 00:00:00 EDT 2008
