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5HT4 Receptor (HTR4) (extracellular) Antibody (ASR-036-200UL) in ICC/IF
Expression of Serotonin receptor 4 in rat PC12 cells - Cell surface detection of Serotonin receptor 4 in intact living rat pheochromocytoma (PC12) cells. A. Extracellular staining of cells using Anti-5HT4 Receptor (HTR4) (extracellular) Antibody , (#ASR-036), (1:100), (red). B. Merge of A with a live view of the cell.
产品信息
ASR-036-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)DVIEKRKFNHNSN, corresponding to amino acid residues 168-180 of rat 5-Hydroxytryptamine receptor 4, 2nd extracellular loop
偶联物
形式
Lyophilized
浓度
0.85 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5 hydroxytryptamine ( serotonin) receptor 4; 5-HT-4; 5-HT4 receptor; 5-HT4 receptor (two splicing variants L and S); 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled; 5-hydroxytryptamine receptor 4; 5HT4; 5HT4 receptor; cardiac 5-HT4 receptor; Serotonin receptor 4
基因别名: 5-HT-4; 5-HT4; 5-HT4R; 5-HT<4L>; 5HTR4; HTR4
UniProt ID: (Human) Q13639, (Rat) Q62758, (Mouse) P97288
Entrez Gene ID: (Human) 3360, (Rat) 25324, (Mouse) 15562
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
serotonin receptor signaling pathway
gamma-aminobutyric acid signaling pathway
chemical synaptic transmission
regulation of appetite
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cell proliferation
cognition
signal transduction
sensory perception of chemical stimulus
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
