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产品信息
PA5-90697
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ACAA2 (NP_0061022)
偶联物
形式
Liquid
浓度
1.09 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806184
产品详细信息
Immunogen sequence: MALLRGVFVV AAKRTPFGAY GGLLKDFTAT DLSEFAAKAA LSAGKVSPET VDSVIMGNVL QSSSDAIYLA RHVGLRVGIP KETPALTINR LCGSGFQSIV NGCQEICVKE AEVVLCGGTE SMSQAPYCVR NVRFGTKLGS DIKLEDSLWV SLTDQHVQLP MAMTAENLAV KHKISREECD KYALQSQQRW KAANDAGYFN DEMAPIEVKT KKGKQTMQVD EHARPQTTLE QLQKLPPVFK KDGTVTAGNA; Positive Samples: LO2, A-549, HeLa, Mouse heart, Mouse liver; Cellular Location: Mitochondrion
靶标信息
ACAA2 (3-Ketoacyl-CoA thiolase) is an enzyme that in humans is encoded by the ACAA2 gene. Acetyl-Coenzyme A acyltransferase 2 is an acetyl-CoA C-acyltransferase enzyme. The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; acetyl-Coenzyme A acyltransferase 2; acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase); Acyl-CoA hydrolase, mitochondrial; beta ketothiolase; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; mitochondrial 3-oxoacyl-Coenzyme A thiolase; T1
基因别名: 0610011L04Rik; ACAA2; AI255831; AI265397; D18Ertd240e; DSAEC
UniProt ID: (Human) P42765, (Mouse) Q8BWT1, (Rat) P13437
Entrez Gene ID: (Human) 10449, (Mouse) 52538, (Rat) 170465
fatty acid metabolic process
cholesterol biosynthetic process
cellular response to hypoxia
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
negative regulation of mitochondrial membrane permeability involved in apoptotic process
acetyl-CoA metabolic process
lipid metabolic process
fatty acid beta-oxidation
metabolic process
