Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-85115
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human ACE.
偶联物
形式
Liquid
浓度
0.58 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792263
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (80%), Rat (80%), Pig (83%), Rabbit (87%), Chimpanzee (99%), Bovine (82%).
Positive Control: mouse lung.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes-the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: ACE; angiotensin 1 converting enzyme 1; angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin I converting enzyme 1; angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript; angiotensin I-converting enzyme (Dipeptidyl carboxypeptidase 1); Angiotensin-converting enzyme; carboxycathepsin; CD143; CD143 antigen; dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase 1 (Angiotensin I-converting enzyme); Dipeptidyl carboxypeptidase I; dipeptidyl peptidase; Kininase II; MGC26566; peptidase P; testicular ECA
基因别名: ACE; ACE1; AW208573; CD143; DCP; DCP1; ICH; MVCD3; StsRR92
UniProt ID: (Human) P12821, (Mouse) P09470, (Rat) P47820
Entrez Gene ID: (Human) 1636, (Mouse) 11421, (Rat) 24310
endopeptidase activity
carboxypeptidase activity
drug binding
metallopeptidase activity
exopeptidase activity
tripeptidyl-peptidase activity
peptidyl-dipeptidase activity
zinc ion binding
chloride ion binding
mitogen-activated protein kinase kinase binding
bradykinin receptor binding
mitogen-activated protein kinase binding
metallodipeptidase activity
actin binding
protein binding
peptidase activity
lytic transglycosylase activity
mannosidase activity
mannosyl-oligosaccharide mannosidase activity
galactosidase activity
glucosidase activity
trehalase activity
fucosidase activity
hexosaminidase activity
amylase activity
hydrolase activity
dextrin alpha-glucosidase activity
starch alpha-glucosidase activity
metal ion binding
beta-glucanase activity
beta-6-sulfate-N-acetylglucosaminidase activity
glucan endo-1,4-beta-glucosidase activity
metalloprotease
protease
protein modifying enzyme
kidney development
blood vessel remodeling
angiotensin maturation
angiotensin catabolic process in blood
regulation of renal output by angiotensin
neutrophil mediated immunity
antigen processing and presentation of peptide antigen via MHC class I
regulation of systemic arterial blood pressure by renin-angiotensin
spermatogenesis
regulation of blood pressure
regulation of smooth muscle cell migration
regulation of vasoconstriction
mononuclear cell proliferation
regulation of vasodilation
hormone catabolic process
peptide catabolic process
beta-amyloid metabolic process
arachidonic acid secretion
heart contraction
regulation of angiotensin metabolic process
hematopoietic stem cell differentiation
positive regulation of protein tyrosine kinase activity
cell proliferation in bone marrow
positive regulation of peptidyl-tyrosine autophosphorylation
regulation of hematopoietic stem cell proliferation
negative regulation of gap junction assembly
positive regulation of peptidyl-cysteine S-nitrosylation
positive regulation of systemic arterial blood pressure
proteolysis
peptide metabolic process
posttranscriptional regulation of gene expression
negative regulation of gene expression
bradykinin catabolic process
sensory perception of pain
organ regeneration
negative regulation of protein binding
positive regulation of protein binding
response to lipopolysaccharide
vasoconstriction
eating behavior
positive regulation of apoptotic process
lung alveolus development
positive regulation of inflammatory response
positive regulation of neurogenesis
angiogenesis involved in coronary vascular morphogenesis
negative regulation of calcium ion import
response to hypoxia
brain development
female pregnancy
aging
male gonad development
lung development
response to nutrient levels
response to laminar fluid shear stress
response to drug
cellular response to glucose stimulus
response to dexamethasone
response to thyroid hormone
