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产品信息
PA1-9070
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the C terminus amino acids QRKQGAGAPTAP (aa 813-824).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2221736
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
靶标信息
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.
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生物信息学
蛋白别名: a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 8; ADAM; ADAM 8; ADAMs; CD156a; Cell surface antigen MS2; Disintegrin and metalloproteinase domain-containing protein 8; human leukocyte differentiation antigen; metalloendopeptidases; MGC134985
基因别名: ADAM8; CD156; CD156a; MS2
UniProt ID: (Human) P78325
Entrez Gene ID: (Human) 101
cell morphogenesis
angiogenesis
leukocyte migration involved in inflammatory response
positive regulation of acute inflammatory response
proteolysis
inflammatory response
positive regulation of protein processing
single organismal cell-cell adhesion
regulation of cell-cell adhesion
extracellular matrix disassembly
positive regulation of T cell differentiation in thymus
activation of MAPK activity involved in innate immune response
negative regulation of neuron apoptotic process
positive regulation of bone resorption
positive regulation of cell adhesion
lymphocyte chemotaxis
positive regulation of protein secretion
positive regulation of membrane protein ectodomain proteolysis
positive regulation of NF-kappaB transcription factor activity
positive regulation of protein kinase B signaling
positive regulation of thymocyte apoptotic process
cellular response to hypoxia
positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
positive regulation of neutrophil extravasation
positive regulation of fibronectin-dependent thymocyte migration
positive regulation of eosinophil migration
