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ADCY1 Antibody (PA5-97241) in WB
Western blot analysis of ADCY1 in extracts of various cell lines. Samples were incubated with ADCY1 Polyclonal antibody (Product # PA5-97241) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-97241
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 470-610 of human ADCY1 (NP_0669391)
偶联物
形式
Liquid
浓度
0.63 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2809043
产品详细信息
Immunogen sequence: NIETFFIVPS HRRKIFPGLI LSDIKPAKRM KFKTVCYLLV QLMHCRKMFK AEIPFSNVMT CEDDDKRRAL RTASEKLRNR SSFSTNVVYT TPGTRVNRYI SRLLEARQTE LEMADLNFFT LKYKHVEREQ KYHQLQDEYF T; Positive Samples: Mouse brain, Mouse kidney; Cellular Location: Cell membrane, Cytoplasm, Membrane, Membrane raft, Multi-pass membrane protein
靶标信息
ADCY1 belongs to the adenylyl cyclase class-4/guanylyl cyclase family. It is a calmodulin-sensitive adenylyl cyclase. ADCY1 may be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3',5'-cyclic AMP synthetase; adenyl cyclase; adenylate cyclase 1 (brain); Adenylate cyclase type 1; Adenylate cyclase type I; Adenylyl cyclase 1; ATP pyrophosphate-lyase 1; barrelless; Ca(2+)/calmodulin-activated adenylyl cyclase
基因别名: AC1; ADCY1; brl; D11Bwg1392e; DFNB44; I-AC; mKIAA4070
UniProt ID: (Human) Q08828, (Mouse) O88444
Entrez Gene ID: (Human) 107, (Mouse) 432530
renal water homeostasis
cAMP biosynthetic process
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
axonogenesis
long-term memory
circadian rhythm
response to lithium ion
cAMP-mediated signaling
activation of protein kinase A activity
response to drug
regulation of circadian rhythm
cellular response to calcium ion
cellular response to glucagon stimulus
cellular response to forskolin
cyclic nucleotide biosynthetic process
intracellular signal transduction
rhythmic process
