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NeoBiotechnologies
ADCY8 (Adenylate Cyclase 8) Monoclonal Antibody (ADCY8/7341)
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产品信息
114-MSM1-P1ABX
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG, kappa
分类
Monoclonal
类型
Antibody
克隆号
ADCY8/7341
抗原
Recombinant fragment (around aa1-200) of human ADCY8 protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive Control:Human brain tissue.
Cellular Location: Cell surface. Multi-pass membrane protein. Cytoplasm.
靶标信息
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AC8; adenylate cyclase 8 (brain); Adenylate cyclase type 8; Adenylate cyclase type VIII; Adenylyl cyclase 8; adenylyl cyclase-8, brain; ATP pyrophosphate-lyase 8; Ca(2+)/calmodulin-activated adenylyl cyclase; epididymis secretory sperm binding protein Li 172mP; HEL-S-172mP
基因别名: AC8; ADCY3; ADCY8; HBAC1
UniProt ID: (Human) P40145
Entrez Gene ID: (Human) 114
renal water homeostasis
cAMP biosynthetic process
signal transduction
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
learning or memory
long-term memory
cAMP-mediated signaling
activation of protein kinase A activity
cellular response to glucagon stimulus
