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产品信息
H00000117-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
2B12
抗原
ADCYAP1R1 (NP_001109, 21 a.a. approximately 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MHSDCIFKKE QAMCLEKIQR ANELMGFNDS SPGCPGMWDN ITCWKPAHVG EMVLVSCPEL FRIFNPDQVW ETETIGESDF GDSNSLDLSD MGVVSRNCTE
靶标信息
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Alternative splicing of two exons of this gene generates four major splice variants, but their full-length nature has not been determined. PACAP receptor type 1 expression has been documented in adipose, adrenal, bone, brain, colon, ganglion, heart, lung, ovary, pancreas, placenta, spleen, and uterus. ESTs have been isolated from brain and nerve libraries.
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生物信息学
蛋白别名: ADCYAP1 R1; ADCYAP1R 1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; PAC 1; PAC1 receptor; Pac1 receptors; PACAP R 1; PACAP Receptor; PACAP receptor 1; PACAP type I receptor; PACAP-R1; PACAP/VIP receptors; PACAP1 R; PACAP1 receptor; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; Pituitary adenylate cyclase-activating polypeptide type I receptor; pvr1
基因别名: ADCYAP1R1; PAC1; PAC1R; PACAPR; PACAPRI
UniProt ID: (Human) P41586
Entrez Gene ID: (Human) 117
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
activation of phospholipase C activity
spermatogenesis
positive regulation of calcium ion transport into cytosol
cAMP-mediated signaling
cell differentiation
positive regulation of cAMP biosynthetic process
response to estradiol
multicellular organismal response to stress
response to drug
response to ethanol
development of primary female sexual characteristics
negative regulation of cell death
positive regulation of inositol phosphate biosynthetic process
