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Application
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ADNP Antibody (PA5-47792) in ICC/IF
Immunocytochemistry analysis of ADNP in immersion fixed RAW 264.7 mouse monocyte/macrophage cell line. Samples were incubated in ADNP polyclonal antibody (Product # PA5-47792) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red, upper panel) and counterstained with DAPI (blue, lower panel). Specific staining was localized to nuclei.
产品信息
PA5-47792
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant mouse ADNP Leu941-Ala1102
偶联物
Unconjugated
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2576251
产品详细信息
In direct ELISAs, approximately 30% cross-reactivity with recombinant human ADNP is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Activity-dependent neuroprotective protein; Activity-dependent neuroprotector homeobox protein; NAP peptide
基因别名: AA589558; Adnp; mKIAA0784
UniProt ID: (Mouse) Q9Z103, (Rat) Q9JKL8
Entrez Gene ID: (Mouse) 11538, (Rat) 64622
transcription, DNA-templated
regulation of transcription, DNA-templated
short-term memory
negative regulation of gene expression
regulation of protein ADP-ribosylation
positive regulation of neuron projection development
positive regulation of cGMP biosynthetic process
negative regulation of protein binding
activation of protein kinase activity
nitric oxide homeostasis
negative regulation of neuron apoptotic process
positive regulation of axon extension
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of synaptic transmission
positive regulation of synapse assembly
response to carbohydrate
response to inorganic substance
cellular response to extracellular stimulus
estrous cycle
