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产品信息
PA5-21004
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 14 amino acid synthetic peptide near the center of human AFP
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11157055
产品详细信息
A suggested positive control is human liver tissue lysate.
PA5-21004 can be used with blocking peptide PEP-1118.
The immunogen is located within amino acids 340 - 390 of AFP.
靶标信息
AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric, dimeric, and trimeric forms. AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: a fetoglobulin; a fetoprotein; Alpha fetoglobulin; Alpha-1-fetoprotein; Alpha-fetoglobulin; Alpha-fetoprotein; alpha-foetoprotein; chloride intracellular channel 6; fetoglobulin; fetoprotein; α fetoglobulin; α fetoprotein
基因别名: AFP; AFPD; FETA; HPAFP
UniProt ID: (Human) P02771, (Mouse) P02772
Entrez Gene ID: (Human) 174, (Rat) 24177, (Mouse) 11576
