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Sequence homology: Cow: 82%; Dog: 85%; Guinea Pig: 91%; Horse: 79%; Human: 100%; Mouse: 91%; Rat: 91%
The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AhR repressor; aryl hydrocarbon hydroxylase regulator; Aryl hydrocarbon receptor repressor; bHLHe77; Class E basic helix-loop-helix protein 77; dioxin receptor repressor
基因别名: AHH; AHHR; AHRR; BHLHE77; KIAA1234
UniProt ID: (Human) A9YTQ3
Entrez Gene ID: (Human) 57491