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产品信息
PA5-142104
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence LTMSVTLSPLRSQ-C (aa 2-14).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2932765
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
靶标信息
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum.
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生物信息学
蛋白别名: A-kinase anchor protein 6; A-kinase anchoring protein alpha; A-kinase anchoring protein beta; anchor protein 6
基因别名: AI482140; Akapalpha; Akapbeta; PRKA
Entrez Gene ID: (Mouse) 238161
positive regulation of protein phosphorylation
regulation of protein kinase A signaling
positive regulation of cell growth
negative regulation of cAMP biosynthetic process
positive regulation of protein phosphatase type 2B activity
cellular protein complex localization
positive regulation of release of sequestered calcium ion into cytosol
positive regulation of NFAT protein import into nucleus
regulation of membrane repolarization
positive regulation of ryanodine-sensitive calcium-release channel activity
positive regulation of cell growth involved in cardiac muscle cell development
positive regulation of calcineurin-NFAT signaling cascade
cellular response to cAMP
cellular response to cytokine stimulus
cellular response to epinephrine stimulus
regulation of cardiac muscle cell contraction
positive regulation of potassium ion transmembrane transport
regulation of relaxation of cardiac muscle
positive regulation of delayed rectifier potassium channel activity
positive regulation of cAMP-dependent protein kinase activity
