Invitrogen

ALDH1A2 Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

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说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (7)
高级验证 (1)

ALDH1A2 Antibody in Immunocytochemistry (ICC/IF)

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ALDH1A2 Antibody (PA5-22377) in ICC/IF

Immunofluorescence analysis of ALDH1A2 was performed using 70% confluent log phase Jurkat cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with ALDH1A2 Polyclonal Antibody (Product # PA5-22377) at 5 µg/mL in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034... View More

ALDH1A2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

PA5-22377

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

免疫细胞化学 (ICC/IF)

5 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 278 and 518 of ALDH1A2 (Uniprot ID#O94788)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.43 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol, 1% BSA

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_11154097

产品详细信息

Recommended positive controls: IMR32, mouse liver, mouse testis, rat testis.

Predicted reactivity: Mouse (97%), Rat (98%), Xenopus laevis (91%), Dog (99%), Chicken (98%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: AL1A2; alcohol dehydrogenase family 1, subfamily A2; alcohol dehydrogenase family 1, subfamily A7; aldehyde dehydrogenase 1 family, member A2; aldehyde dehydrogenase 1A2; Aldehyde dehydrogenase family 1 member A2; aldehyde dehydrogenase family 1, subfamily A2; ALDH1A2; RALDH 2; RALDH(II); ralDH2; Retinal dehydrogenase 2; retinal dehydrogenase, type II; retinaldehyde dehydrogenase 2; Retinaldehyde-specific dehydrogenase type 2

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基因别名: ALDH1A2; Aldh1a7; AV116159; RALDH(II); Raldh-2; Raldh1; RALDH2; RALDH2-T

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UniProt ID: (Human) O94788, (Mouse) Q62148, (Rat) Q63639

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Entrez Gene ID: (Human) 8854, (Mouse) 19378, (Rat) 116676

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功能

retinal dehydrogenase activity 3-chloroallyl aldehyde dehydrogenase activity aldehyde dehydrogenase (NAD) activity retinal binding oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor dehydrogenase oxidoreductase metabolite interconversion enzyme

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