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产品信息
PA5-19326
产品规格
种属反应
Human,
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (RYPPSPAKMTQH) corresponding to the C-terminus amino acids of ALDH3A1 (aa 442-453).
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10980559
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorption of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alcohol dehydrogenase family 3, subfamily A1; Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family, member A1; aldehyde dehydrogenase 3, stomach cytosolic (class 3); Aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A1; aldehyde dehydrogenase isozyme 3; aldehyde dehydrogenase type III; Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHIII; Dioxin-inducible aldehyde dehydrogenase 3; MGC10406; stomach aldehyde dehydrogenase
基因别名: Ahd-4; Ahd4; Aldh; ALDH3; ALDH3A1; Aldh4; ALDHIII
UniProt ID: (Human) P30838, (Mouse) P47739
Entrez Gene ID: (Human) 218, (Mouse) 11670
3-chloroallyl aldehyde dehydrogenase activity
aldehyde dehydrogenase (NAD) activity
aldehyde dehydrogenase [NAD(P)+] activity
protein binding
alcohol dehydrogenase (NADP+) activity
benzaldehyde dehydrogenase (NAD+) activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
dehydrogenase
