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This target displays homology in the following species: Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 93%
Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Amer2; APC membrane recruitment protein 2; family with sequence similarity 123, member A; Protein FAM123A
基因别名: 2600011E07Rik; Amer2; Fam123a
UniProt ID: (Mouse) Q8CCJ4
Entrez Gene ID: (Mouse) 72125