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产品信息
H00027063-B02P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ANKRD1 (NP_055206.2, 1 a.a. approximately 319 a.a) full-length human protein.
偶联物
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MMVLKVEELV TGKKNGNGEA GEFLPEDFRD GEYEAAVTLE KQEDLKTLLA HPVTLGEQQW KSEKQREAEL KKKKLEQRSK LENLEDLEII IQLKKRKKYR KTKVPVVKEP EPEIITEPVD VPTFLKAALE NKLPVVEKFL SDKNNPDVCD EYKRTALHRA CLEGHLAIVE KLMEAGAQIE FRDMLESTAI HWASRGGNLD VLKLLLNKGA KISARDKLLS TALHVAVRTG HYECAEHLIA CEADLNAKDR EGDTPLHDAV RLNRYKMIRL LIMYGADLNI KNCAGKTPMD LVLHWQNGTK AIFDSLRENS YKTSRIATF
靶标信息
The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ankyrin repeat domain 1 (cardiac muscle); Ankyrin repeat domain-containing protein 1; Cardiac ankyrin repeat protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; liver ankyrin repeat domain 1
基因别名: ALRP; ANKRD1; bA320F15.2; C-193; C193; CARP; CVARP; HA1A2; MCARP
UniProt ID: (Human) Q15327
Entrez Gene ID: (Human) 27063
negative regulation of transcription from RNA polymerase II promoter
positive regulation of neuron projection development
cellular response to drug
skeletal muscle cell differentiation
response to muscle stretch
muscle cell differentiation
positive regulation of apoptotic process
positive regulation of DNA damage response, signal transduction by p53 class mediator
sarcomere organization
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein secretion
cardiac muscle tissue morphogenesis
cellular response to lipopolysaccharide
cellular response to mechanical stimulus
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to organic cyclic compound
cellular response to hypoxia
cellular response to transforming growth factor beta stimulus
negative regulation of DNA biosynthetic process
