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Application
FIGURE: 1 / 1
ANKS1B Antibody (PA5-121141) in WB
Western blot analysis of ANKS1B in extracts of various cell lines. Samples were incubated with ANKS1B Polyclonal antibody (Product # PA5-121141) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-121141
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 261-510 of human ANKS1B (NP_858056.2).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.45 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2914713
Product Specific Information
Positive test controls include: A-549, Mouse liver. The target is usually found in the following locations: Cajal body, Cell junction, Cell projection, Cytoplasm, Nucleus, dendritic spine, postsynaptic cell membrane, postsynaptic density, synapse.
Immunogen sequence: GFPFSAIHQV HNTGDWGEPS ITLRPPNEAT ASTPVQYWQH HPEKLIFQSC DYKAFYLGSM LIKELRGTES TQDACAKMRA NCQKSTEQMK KVPTIILSVS YKGVKFIDAT NKNIIAEHEI RNISCAAQDP EDLSTFAYIT KDLKSNHHYC HVFTAFDVNL AYEIILTLGQ AFEVAYQLAL QARKGGHSST LPESFENKPS KPIPKPRVSI RKSVQIDPSE QKTLANLPWI VEPGQEAKRG INTKYETTIF
Target Information
This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization) have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AIDA-1; amyloid-beta precursor protein intracellular domain associated protein 1; Amyloid-beta protein intracellular domain-associated protein 1; Ankyrin repeat and sterile alpha motif domain-containing protein 1B; cajalin 2; E2A-PBX1-associated protein; EB-1; MGC26087
Gene Aliases: AIDA; AIDA-1; AIDA-1b; ANKS1B; ANKS2; C030032C09Rik; cajalin-2; E530015N03Rik; EB-1; EB1; ENSMUSG00000078431; Gm10937; Gm1555; RGD1565556
UniProt ID: (Human) Q7Z6G8, (Mouse) Q8BIZ1
Entrez Gene ID: (Human) 56899, (Mouse) 77531, (Rat) 314721
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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