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产品信息
H00116519-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
APOA5 (AAI01790.1, 1 a.a. approximately 366 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MASMAAVLTW ALALLSAFSA TQARKGFWDY FSQTSGDKGR VEQIHQQKMA REPATLKDSL EQDLNNMNKF LEKLRPLSGS EAPRLPQDPV GMRRQLQEEL EEVKARLQPY MAEAHELVGW NLEGLRQQLK PYTMDLMEQV ALRVQELQEQ LRVVGEDTKA QLLGGVDEAW ALLQGLQSRV VHHTGRFKEL FHPYAESLVS GIGRHVQELH RSVAPHAPAS PARLSRCVQV LSRKLTLKAK ALHARIQQNL DQLREELSRA FAGTGTEEGA GPDPQMLSEE VRQRLQAFRQ DTYLQIAAFT RAIDQETEEV QQQLAPPPPG HSAFAPEFQQ TDSGKVLSKL QARLDDLWED ITHSLHDQGH SHLGDP
靶标信息
Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but several evidences from vitro studies indicate that this apolipoprotein involves in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Apo-AV; Apolipoprotein A-V; apolipoprotein A-V precursor variant 3; Apolipoprotein A5; apolipoprotein AV; FLJ97995; MGC126836; MGC126838; Regeneration-associated protein 3
基因别名: APOA5; APOAV; RAP3; UNQ411/PRO773
UniProt ID: (Human) Q6Q788
Entrez Gene ID: (Human) 116519
phospholipid binding
enzyme activator activity
heparin binding
lipid binding
cholesterol binding
cholesterol transporter activity
enzyme binding
phosphatidylcholine binding
lipase binding
low-density lipoprotein particle receptor binding
phosphatidylcholine-sterol O-acyltransferase activator activity
lipase activator activity
lipoprotein lipase activator activity
lipoprotein particle receptor binding
apolipoprotein
triglyceride metabolic process
cholesterol biosynthetic process
lipid transport
positive regulation of cholesterol esterification
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
triglyceride catabolic process
regulation of intestinal cholesterol absorption
neuron projection regeneration
cholesterol efflux
phospholipid efflux
triglyceride-rich lipoprotein particle remodeling
high-density lipoprotein particle assembly
lipoprotein metabolic process
tissue regeneration
cholesterol homeostasis
reverse cholesterol transport
positive regulation of fatty acid biosynthetic process
phosphatidylcholine metabolic process
positive regulation of receptor-mediated endocytosis
positive regulation of lipid catabolic process
positive regulation of lipoprotein lipase activity
acylglycerol homeostasis
triglyceride homeostasis
