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APOBEC1 Antibody (PA5-109400) in WB
Western blot analysis of APOBEC1 in extracts of Mouse spleen. Samples were incubated with APOBEC1 Polyclonal antibody (Product # PA5-109400) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.
产品信息
PA5-109400
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human APOBEC1 (NP_001291495).
偶联物
形式
Liquid
浓度
1.51 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2854811
产品详细信息
Immunogen sequence: MTSEKGPSTG DPTLRRRIEP WEFDVFYDPR ELRKEACLLY EIKWGMSRKI WRSSGKNTTN HVEVNFIKKF TSERDFHPSM
靶标信息
This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor and APOBEC1 stimulating protein . This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: APOBEC-1; apolipoprotein B editing complex 1; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide 1; C->U-editing enzyme APOBEC-1; mRNA(cytosine(6666)) deaminase 1
基因别名: Apobec1; Cdar1
UniProt ID: (Mouse) P51908
Entrez Gene ID: (Mouse) 11810
catalytic activity
GTP cyclohydrolase activity
cytidine deaminase activity
cytosine deaminase activity
protein binding
tRNA-specific adenosine deaminase activity
zinc ion binding
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
AU-rich element binding
N-cyclopropylmelamine deaminase activity
N-cyclopropylammeline deaminase activity
N-cyclopropylammelide alkylamino hydrolase activity
2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity
tRNA-specific adenosine-37 deaminase activity
archaeal-specific GTP cyclohydrolase activity
metal ion binding
tRNA-specific adenosine-34 deaminase activity
RNA processing factor
mRNA processing
response to osmotic stress
cytidine deamination
response to gamma radiation
cytidine to uridine editing
mRNA modification
regulation of cell proliferation
lipoprotein metabolic process
lipoprotein biosynthetic process
response to drug
lipoprotein transport
response to ethanol
mRNA stabilization
response to calcium ion
defense response to virus
DNA cytosine deamination
DNA demethylation
negative regulation of methylation-dependent chromatin silencing
