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产品信息
PA5-75483
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 67-112 of Human APOBEC3A.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719211
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
PHO1 a member of the cytidine deaminase gene family. The PHO1 gene is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. This gene encodes a protein that lacks the zinc binding activity and may be an expressed pseudogene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A3A; apolipoprotein B editing complex 3; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3A; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A; Apolipoprotein B mRNA-editing complex 3; Arp3; CEM-15; CEM15; DNA dC->dU-editing enzyme APOBEC-3; DNA dC->dU-editing enzyme APOBEC-3A; PHO-1; pho1; phorbolin 1; Phorbolin-1; Phorbolin1; probable DNA dC->dU-editing enzyme APOBEC-3A; recovery from Friend virus 3
基因别名: A3A; Apobec3; APOBEC3A; ARP3; BC003314; bK150C2.1; Cem15; PHRBN; Rfv3
UniProt ID: (Human) P31941, (Mouse) Q99J72
Entrez Gene ID: (Human) 200315, (Mouse) 80287
cytidine deaminase activity
protein binding
zinc ion binding
deoxycytidine deaminase activity
catalytic activity
GTP cyclohydrolase activity
tRNA-specific adenosine deaminase activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
N-cyclopropylmelamine deaminase activity
N-cyclopropylammeline deaminase activity
N-cyclopropylammelide alkylamino hydrolase activity
2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity
tRNA-specific adenosine-37 deaminase activity
archaeal-specific GTP cyclohydrolase activity
poly(A) RNA binding
metal ion binding
tRNA-specific adenosine-34 deaminase activity
RNA processing factor
cytidine deamination
negative regulation of transposition
clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine
negative regulation of viral genome replication
innate immune response
defense response to virus
DNA cytosine deamination
cellular response to xenobiotic stimulus
DNA demethylation
hematopoietic progenitor cell differentiation
immune system process
metabolic process
