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APOC2 Antibody (PA5-102480) in IHC (P)
Immunohistochemistry analysis of APOC2 in mouse liver tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with APOC2 polyclonal antibody (Product # PA5-102480) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-102480
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human APOC2(Accession P02655), corresponding to amino acid residues G2-K52.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2851882
产品详细信息
Antibody detects endogenous levels of total APOC2.
靶标信息
Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins. The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages. The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: APC 2; APO C2; Apo CII; Apo-CII; APOC 2; ApoC II; apoC-II; APOC2 protein; ApoCII; Apolipoprotein C II; Apolipoprotein C-II; Apolipoprotein C2; Apolipoprotein CII; ApolipoproteinCII; MGC75082
基因别名: APC2; APO-CII; APOC-II; APOC2; RGD1560725
UniProt ID: (Human) P02655, (Mouse) Q05020, (Rat) G3V8D4
Entrez Gene ID: (Human) 344, (Mouse) 11813, (Rat) 292697
retinoid metabolic process
positive regulation of phospholipase activity
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
negative regulation of very-low-density lipoprotein particle clearance
lipid catabolic process
negative regulation of cholesterol transport
cholesterol efflux
phospholipid efflux
triglyceride-rich lipoprotein particle remodeling
chylomicron remodeling
very-low-density lipoprotein particle remodeling
chylomicron remnant clearance
high-density lipoprotein particle clearance
lipoprotein metabolic process
cholesterol homeostasis
negative regulation of catalytic activity
reverse cholesterol transport
positive regulation of fatty acid biosynthetic process
negative regulation of lipid metabolic process
negative regulation of receptor-mediated endocytosis
positive regulation of lipoprotein lipase activity
positive regulation of phospholipid catabolic process
triglyceride homeostasis
lipid metabolic process
transport
lipid transport
lipoprotein transport
response to drug
positive regulation of catalytic activity
