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产品信息
PA5-115948
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SORBS2(Accession O94875), corresponding to amino acid residues Q600-H650.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2900582
产品详细信息
Antibody detects endogenous levels of total SORBS2.
靶标信息
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology(SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Arg binding protein 2; Arg-binding protein 2; Arg/Abl-interacting protein 2; Arg/Abl-interacting protein ArgBP2; ArgBP2; Sorbin; Sorbin and SH3 domain-containing protein 2
基因别名: 2010203O03Rik; 9430041O17Rik; A530071H08; ARGBP2; KIAA0777; mKIAA0777; PRO0618; SORBS2
UniProt ID: (Human) O94875, (Mouse) Q3UTJ2
Entrez Gene ID: (Human) 8470, (Mouse) 234214
