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产品信息
MA5-42664
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4F2G6
抗原
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ARPC2 (O15144).
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2911805
产品详细信息
Positive test controls include: HepG2, Mouse spleen, Mouse stomach, Mouse thymus, Rat lung. The target is usually found in the following locations: Cell junction, Cell projection, Cytoplasm, cytoskeleton, synapse, synaptosome.
Immunogen sequence: FSHREPPLEL KDTDAAVGDN IGYITFVLFP RHTNASARDN TINLIHTFRD YLHYHIKCSK AYIHTRMRAK TSDFLKVLNR ARPDAEKKEM KTITGKTFSS R
靶标信息
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: actin related protein 2/3 complex subunit 2, 34kDa; actin related protein 2/3 complex, subunit 2, 34kDa; Actin-related protein 2/3 complex subunit 2; actin-related protein 2/3 complex subunit 2 {ECO:0000250|UniProtKB:O15144}; Arp2/3 complex 34 kDa subunit; arp2/3 complex 34 kDa subunit {ECO:0000250|UniProtKB:O15144}; ARP2/3 protein complex subunit 34; arpc2 {ECO:0000250|UniProtKB:O15144}; p34-ARC; p34-ARC {ECO:0000250|UniProtKB:O15144}; testis tissue sperm-binding protein Li 53e
基因别名: 2210023N03Rik; 34kDa; ARC34; ARPC2; p34-Arc; PNAS-139; PRO2446
UniProt ID: (Human) O15144, (Mouse) Q9CVB6
Entrez Gene ID: (Human) 10109, (Rat) 301511, (Mouse) 76709
positive regulation of lamellipodium assembly
positive regulation of actin filament polymerization
Arp2/3 complex-mediated actin nucleation
positive regulation of substrate adhesion-dependent cell spreading
movement of cell or subcellular component
Fc-gamma receptor signaling pathway involved in phagocytosis
ephrin receptor signaling pathway
regulation of actin filament polymerization
