Search Thermo Fisher Scientific
图: 1 / 2
Sequence of this protein is as follows: MKTGHFEIVT MLLATMILVD IFQVKAEVLD MADNAFDDEY LKCTDRMEIK YVPQLLKEEK ASHQQLDTVW ENAKAKWAAR KTQIFLPMNF KDNHGIALMA YISEAQEQTP FYHLFSEAVK MAGQSREDYI YGFQFKAFHF YLTRALQLLR KPCEASSKTV VYRTSQGTSF TFGGLNQARF GHFTLAYSAK PQAANDQLTV LSIYTCLGVD IENFLDKESE RITLIPLNEV FQVSQEGAGN NLILQSINKT CSHYECAFLG GLKTENCIEN LEYFQPIYVY NPGEKNQKLE DHSEKNWKLE DHGEKNQKLE DHGVKILEPT QIPEDKSQGN INNPTPGPVP VPGPKSHPSA SSGKLLLPQF GMVIILISVS AINLFVAL
Mono-ADP-ribosylation involves the transfer of the ADP-ribose moiety from NAD+ to a specific amino acid in the target protein. The rodent mono-ADP-ribosyltransferase RT6 is a glycosylphosphatidylinositol (GPI)-anchored membrane protein specifically expressed at the cell surface of rat and mouse T lymphocytes. The predicted 367-amino acid human ART3 protein has an estimated molecular mass of 41.5 kD and contains a hydrophobic peptide signal at its N terminus, 3 consensus motifs specific to enzymes catalyzing ADP-ribose transfer, a hydrophobic C-terminal sequence characteristic of a GPI-anchored protein, a novel motif repeated 3 times at its C terminus, and 1 potential glycosylation site.1 The ART3 and rodent RT6 proteins share 35% amino acid identity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ADP-ribosyltransferase C2 and C3 toxin-like 3; ART3 mono(ADP-ribosyl)transferase; ARTC3; Ecto-ADP-ribosyltransferase 3; Mono(ADP-ribosyl)transferase 3; mono-ADP-ribosyltransferase; mono-ADP-ribosyltransferase 3; NAD(P)(+)--arginine ADP-ribosyltransferase 3
基因别名: 4930569O04Rik; ART3; ARTC3; TMART
UniProt ID: (Human) Q13508, (Mouse) Q8R2G4
Entrez Gene ID: (Human) 419, (Mouse) 109979
分子生物学功能: transferase