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产品信息
PA5-110350
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Septin 4 (NP_5363411)
偶联物
形式
Liquid
浓度
1.08 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855761
产品详细信息
Immunogen sequence: MIKRFLEDTT DDGELSKFVK DFSGNASCHP PEAKTWASRP QVPEPRPQAP DLYDDDLEFR PPSRPQSSDN QQYFCAPAPL SPSARPRSPW GKLDPYDSSE
靶标信息
Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
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生物信息学
蛋白别名: 4-Sep; apoptosis-related protein in the TGF-beta signaling pathway; Bradeion beta; Brain protein H5; CE5B3 beta; Cell division control-related protein 2; cell division control-related protein 2b; cerebral protein 7; expression gene 3 in rat visual cortex; expression gene 3-1 in rat visual cortex; hCDCREL-2; M-Septin; peanut-like 2; peanut-like 2 homolog; Peanut-like protein 2; septin H5; Septin-4; septin-M
基因别名: ARTS; Bh5; BRADEION; C17orf47; CE5B3; EG3-1RVC; EG3RVC; Gm11492; H5; hCDCREL-2; hucep-7; MART; OTTMUSG00000001265; PNUTL2; SEP4; SEPT4; SEPTIN4
UniProt ID: (Human) O43236, (Mouse) P28661
Entrez Gene ID: (Human) 5414, (Mouse) 18952, (Rat) 287606
apoptotic process
cell cycle
brain development
sperm mitochondrion organization
positive regulation of protein ubiquitination
regulation of apoptotic process
positive regulation of apoptotic process
sperm capacitation
cell division
positive regulation of intrinsic apoptotic signaling pathway
spermatid development
