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产品信息
PA5-120685
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-412 of human ASS1 (NP_446464.1).
偶联物
形式
Liquid
浓度
2.26 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914257
产品详细信息
Positive test controls include: LO2, HeLa, Mouse heart, Mouse kidney, Rat kidney.^M
^M
Immunogen sequence: MSSKGSVVLA YSGGLDTSCI LVWLKEQGYD VIAYLANIGQ KEDFEEARKK ALKLGAKKVF IEDVSREFVE EFIWPAIQSS ALYEDRYLLG TSLARPCIAR KQVEIAQREG AKYVSHGATG KGNDQVRFEL SCYSLAPQIK VIAPWRMPEF YNRFKGRNDL MEYAKQHGIP IPVTPKNPWS MDENLMHISY EAGILENPKN QAPPGLYTKT QDPAKAPNTP DILEIEFKKG VPVKVTNVKD GTTHQTSLEL FMYLNEVAGK HGVGRIDIVE NRFIGMKSRG IYETPAGTIL YHAHLDIEAF TMDREVRKIK QGLGLKFAEL VYTGFWHSPE CEFVRHCIAK SQERVEGKVQ VSVLKGQVYI LGRESPLSLY NEELVSMNVQ GDYEPTDATG FININSLRLK EYHRLQSKVT AK
靶标信息
The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Argininosuccinate synthase; argininosuccinate synthetase 1; arginosuccinate synthetase 1; Citrulline--aspartate ligase; citrulline-aspartate ligase; RP11-618A20.2
基因别名: AA408052; ASS; Ass-1; ASS1; ASSA; CTLN1; fold
UniProt ID: (Human) P00966, (Rat) P09034, (Mouse) P16460
Entrez Gene ID: (Human) 445, (Rat) 25698, (Mouse) 11898
urea cycle
citrulline metabolic process
argininosuccinate metabolic process
kidney development
liver development
arginine biosynthetic process
aspartate metabolic process
acute-phase response
midgut development
aging
response to nutrient
response to zinc ion
response to mycotoxin
response to estradiol
response to drug
positive regulation of nitric oxide biosynthetic process
response to growth hormone
diaphragm development
response to fatty acid
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to ammonium ion
cellular response to cAMP
cellular response to interferon-gamma
cellular response to tumor necrosis factor
cellular response to glucagon stimulus
cellular response to oleic acid
cellular response to amine stimulus
cellular response to laminar fluid shear stress
cellular response to dexamethasone stimulus
negative regulation of leukocyte cell-cell adhesion
response to toxic substance
response to amine
response to lipopolysaccharide
response to amino acid
response to peptide hormone
response to steroid hormone
response to glucocorticoid
cellular amino acid biosynthetic process
