Invitrogen

ASS1 Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

2 篇参考文献

查看其他20个ASS1抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (5)
高级验证 (2)

ASS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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ASS1 Antibody (PA5-82740) in IHC (P)

Immunohistochemical analysis of ASS1 in human skin using ASS1 Polyclonal Antibody (Product # PA5-82740) shows moderate cytoplasmic positivity in a subset of squamous epithelial cells.

Product Image Gallery

ASS1 Antibody — Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of ASS1 was observed specifically in MCF-7 cells and in U-251MG cells using anti-ASS1 Polyclonal Antibody (Product #PA5-82740) in western blot. The relative expression levels of ASS1 within each cell line is shown using RNA-Seq. {RE}

产品信息

PA5-82740

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:1,000-1:2,500

免疫组化（冰冻） (IHC (F))

查看1篇已发表文章 1篇已发表文章

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human ASS1. Recombinant protein control fragment (Product #RP-92951).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Anitgen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2789896

产品详细信息

Immunogen sequence: AKQHGIPIPV TPKNPWSMDE NLMHISYEAG ILENPKNQAP PGLYTKTQDP AKAPNTPDIL EIEFKKGVPV KVTNVKDG

靶标信息

The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Characterization of the humanized FRG mouse model and development of an AAV-LK03 variant with improved liver lobular biodistribution.

Molecular therapy. Methods & clinical development

Cabanes-Creus M,Navarro RG,Liao SHY,Scott S,Carlessi R,Roca-Pinilla R,Knight M,Baltazar G,Zhu E,Jones M,Denisenko E,Forrest ARR,Alexander IE,Tirnitz-Parker JEE,Lisowski L

PA5-82740 was used in Immunohistochemistry (Frozen), Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that fine-tuning the HSPG attachment profile of AAV vectors can be a powerful tool for engineering their liver lobular transduction profiles.

Thu Mar 09 00:00:00 UTC 2023

A human kidney and liver organoid-based multi-organ-on-a-chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell-derived extracellular vesicles.

Journal of extracellular vesicles

Nguyen VVT,Ye S,Gkouzioti V,van Wolferen ME,Yengej FY,Melkert D,Siti S,de Jong B,Besseling PJ,Spee B,van der Laan LJW,Horland R,Verhaar MC,van Balkom BWM

PA5-82740 was used in Immunohistochemistry to develop a multi-organ-on-a-chip (MOC) model that combines human kidney and liver organoids connected by microfluidic channels to study the therapeutic effects and biodistribution of mesenchymal stromal cell-derived small extracellular vesicles (MSC-sEVs).

Tue Nov 01 00:00:00 UTC 2022

生物信息学

蛋白别名: Argininosuccinate synthase; argininosuccinate synthetase 1; Citrulline--aspartate ligase; citrulline-aspartate ligase; RP11-618A20.2

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基因别名: ASS; ASS1; CTLN1

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UniProt ID: (Human) P00966

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Entrez Gene ID: (Human) 445

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功能

argininosuccinate synthase activity protein binding ATP binding toxic substance binding amino acid binding identical protein binding poly(A) RNA binding ligase

参与通路

ASS1 Polyclonal Antibody

ASS1 Antibody (PA5-82740) in IHC (P)

产品信息

PA5-82740

免疫印迹 (WB)

免疫组化 (IHC)

免疫组化（石蜡） (IHC (P))

免疫组化（冰冻） (IHC (F))

免疫细胞化学 (ICC/IF)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

RRID

产品详细信息

靶标信息

生物信息学

性能保障

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