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Recommended positive controls: 293T, A431, Jurkat, Raji.
Predicted reactivity: Mouse (89%), Rat (88%), Chicken (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Arginyl-tRNA-protein transferase (ATE1), also designated arginyltransferase 1, belongs to the R-transferase family of proteins. In order for a protein to be degraded via the ubiquitin pathway, arginylation of the protein is required. ATE1 plays an important role in this process, as it is important for the posttranslational conjugation of arginine to the N-terminal aspartate-, glutamate- and possibly cystine-contaning substrates. ATE1 is a 518 amino acid protein. Alternative splicing results in two distinct isoforms. ATE1, which is found as a monomer, can localize to the cytoplasm and/or the nucleus.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Arginine-tRNA--protein transferase 1; Arginyl-tRNA--protein transferase 1; arginyl-tRNA-protein transferase; Arginyltransferase 1; R-transferase 1
基因别名: ATE1
UniProt ID: (Human) O95260
Entrez Gene ID: (Human) 11101