Invitrogen

ATP1B1 Polyclonal Antibody

ATP1B1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 8

ATP1B1 Antibody (PA5-29719) in IHC (P)

Sodium Potassium ATPase Beta 1 antibody detects ATP1B1 protein at membrane on Cal27 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Cal27 xenograft. Sodium Potassium ATPase Beta 1 antibody (Product # PA5-29719) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.

Product Image Gallery

产品信息

PA5-29719

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 83 and 303 of Human Sodium Potassium ATPase Beta 1

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol, 1% BSA

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2547193

产品详细信息

Recommended positive controls: K562, HL-60, mouse brain, Rat brain.

Predicted reactivity: Mouse (90%), Rat (92%), Dog (91%), Pig (89%), Rabbit (87%), Sheep (91%), Rhesus Monkey (96%), Chimpanzee (99%), Guinea pig (86%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: adenosinetriphosphatase; ATPase, Na+/K+ transporting, beta 1 polypeptide; Beta 1-subunit of Na(+),K(+)-ATPase; MGC1798; Na+/K+ ATPase Beta; Na, K-ATPase beta-1 polypeptide; Na,K-ATPase beta 1 subunit; OTTHUMP00000032537; OTTHUMP00000032538; Sodium Potassium ATPase; sodium pump subunit beta-1; sodium-potassium ATPase subunit beta 1 (non-catalytic); sodium/potassium ATPase beta subunit; sodium/potassium-dependent ATPase beta-1 subunit; Sodium/potassium-dependent ATPase subunit beta-1; sodium/potassium-transporting ATPase beta-1 chain; Sodium/potassium-transporting ATPase subunit beta-1

查看更多收起

基因别名: ATP1B; ATP1B1; Atp4b; Atpb; Atpb-1; ATPBS; NKbeta1

查看更多收起

UniProt ID: (Human) Q5TGZ3, (Rat) P07340, (Mouse) P14094

查看更多收起

Entrez Gene ID: (Human) 481, (Rat) 25650, (Mouse) 11931

查看更多收起

功能