Invitrogen

ATP1B2 Polyclonal Antibody

ATP1B2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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ATP1B2 Antibody (PA5-26279) in IHC (P)

Immunohistochemistry analysis of ATP1B2 in formalin-fixed and paraffin-embedded human hepatocarcinoma. Samples were incubated with ATP1B2 polyclonal antibody (Product # PA5-26279) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

ATP1B2 Antibody in Flow Cytometry (Flow)

ATP1B2 Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)

ATP1B2 Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC)

ATP1B2 Antibody in Immunohistochemistry, Peptide array (IHC, ARRAY)

ATP1B2 Antibody in Western Blot, Flow Cytometry (WB, Flow)

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产品信息

PA5-26279

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

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免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

1:50-1:100

免疫细胞化学 (ICC/IF)

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流式细胞分析 (Flow)

1:10-1:50

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肽阵列 (Array)

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产品规格

种属反应

Human

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 115-141 amino acids from the central region of human ATP1B2

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2543779

产品详细信息

This antibody is predicted to react with bovine, mouse, rat and rabbit based on sequence homology.

靶标信息

This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The exact function of the beta-2 subunit is not known. Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression.

BMC cancer

Jiang Q,Xie Q,Hu C,Yang Z,Huang P,Shen H,Schachner M,Zhao W

PA5-26279 was used in Immunohistochemistry to study the role of adhesion molecules on glia (AMOG) via modulation of L1 expression in glial tumours.

Thu Sep 12 00:00:00 EDT 2019

Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression.

BMC cancer

Jiang Q,Xie Q,Hu C,Yang Z,Huang P,Shen H,Schachner M,Zhao W

PA5-26279 was used in Immunohistochemistry to study the role of adhesion molecules on glia (AMOG) via modulation of L1 expression in glial tumours.

Thu Sep 12 00:00:00 EDT 2019

Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression.

BMC cancer

Jiang Q,Xie Q,Hu C,Yang Z,Huang P,Shen H,Schachner M,Zhao W

PA5-26279 was used in Immunohistochemistry to study the role of adhesion molecules on glia (AMOG) via modulation of L1 expression in glial tumours.

Thu Sep 12 00:00:00 EDT 2019

Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression.

BMC cancer

Jiang Q,Xie Q,Hu C,Yang Z,Huang P,Shen H,Schachner M,Zhao W

PA5-26279 was used in Immunohistochemistry to study the role of adhesion molecules on glia (AMOG) via modulation of L1 expression in glial tumours.

Thu Sep 12 00:00:00 EDT 2019

Identification of the retinoschisin-binding site on the retinal Na/K-ATPase.

PloS one

Plössl K,Straub K,Schmid V,Strunz F,Wild J,Merkl R,Weber BHF,Friedrich U

Published figure using ATP1B2 polyclonal antibody (Product # PA5-26279) in Western Blot

Tue Jan 14 00:00:00 EST 2020

Identification of the retinoschisin-binding site on the retinal Na/K-ATPase.

PloS one

Plössl K,Straub K,Schmid V,Strunz F,Wild J,Merkl R,Weber BHF,Friedrich U

Published figure using ATP1B2 polyclonal antibody (Product # PA5-26279) in Western Blot

Tue Jan 14 00:00:00 EST 2020

Retinoschisin is linked to retinal Na/K-ATPase signaling and localization.

Molecular biology of the cell

Plössl K,Royer M,Bernklau S,Tavraz NN,Friedrich T,Wild J,Weber BHF,Friedrich U

PA5-26279 was used in Immunohistochemistry to study the influence of retinoschisin on the functionality of the Na/K-ATPase.

Tue Aug 01 00:00:00 EDT 2017

Retinoschisin is linked to retinal Na/K-ATPase signaling and localization.

Molecular biology of the cell

Plössl K,Royer M,Bernklau S,Tavraz NN,Friedrich T,Wild J,Weber BHF,Friedrich U

PA5-26279 was used in Immunohistochemistry to study the influence of retinoschisin on the functionality of the Na/K-ATPase.

Tue Aug 01 00:00:00 EDT 2017

Retinoschisin is linked to retinal Na/K-ATPase signaling and localization.

Molecular biology of the cell

Plössl K,Royer M,Bernklau S,Tavraz NN,Friedrich T,Wild J,Weber BHF,Friedrich U

PA5-26279 was used in Immunohistochemistry to study the influence of retinoschisin on the functionality of the Na/K-ATPase.

Tue Aug 01 00:00:00 EDT 2017

A SINE Insertion in ATP1B2 in Belgian Shepherd Dogs Affected by Spongy Degeneration with Cerebellar Ataxia (SDCA2).

G3 (Bethesda, Md.)

Mauri N,Kleiter M,Dietschi E,Leschnik M,Högler S,Wiedmer M,Dietrich J,Henke D,Steffen F,Schuller S,Gurtner C,Stokar-Regenscheit N,O'Toole D,Bilzer T,Herden C,Oevermann A,Jagannathan V,Leeb T

PA5-26279 was used in Immunohistochemistry to identify ∼10.6 Mb critical interval on chromosome 5 in a Malinois family with four puppies affected by cerebellar dysfunction.

Mon Aug 07 00:00:00 EDT 2017

生物信息学

蛋白别名: Adhesion molecule in glia; adhesion molecule on glia; AMOG; ATPase, Na+/K+ transporting, beta 2 polypeptide; Na, K-ATPase beta-2 polypeptide; Sodium Potassium ATPase; sodium pump subunit beta-2; sodium-potassium ATPase subunit beta 2 (non-catalytic); sodium/potassium-dependent ATPase beta-2 subunit; Sodium/potassium-dependent ATPase subunit beta-2; sodium/potassium-transporting ATPase beta-2 chain; Sodium/potassium-transporting ATPase subunit beta-2

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基因别名: AMOG; ATP1B2

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UniProt ID: (Human) P14415

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Entrez Gene ID: (Human) 482

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功能

ATPase activator activity sodium:potassium-exchanging ATPase activity protein binding ATPase binding primary active transporter

参与通路