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ATRIP Antibody (PA5-96590) in WB
Western blot analysis of ATRIP in extracts of various cell lines. Samples were incubated with ATRIP Polyclonal antibody (Product # PA5-96590) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-96590
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ATRIP (NP_5690551)
偶联物
Unconjugated
形式
Liquid
浓度
1.87 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2808392
产品详细信息
Immunogen sequence: MAGTSAPGSK RRSEPPAPRP GPPPGTGHPP SKRARGFSAA AAPDPDDPFG AHGDFTADDL EELDTLASQA LSQCPAAARD VSSDHKVHRL LDGMSKNPSG KNRETVPIKD NFELEVLQAQ YKELKEKMKV MEEEVLIKNG EIKILRDSLH QTESVLEEQR RSHFLLEQEK TQALSDKEKE FSKKLQSLQS ELQFKDAEMN ELRTKLQTSE RANKLAAPSV SHVSPRKNPS VVIKPEACSP QFGKTSFPTK ESFSANMSLP; Positive Samples: HepG2, Jurkat, HeLa, Mouse brain, Mouse heart; Cellular Location: Nucleus
靶标信息
ATRIP is an 86 kDa protein that is phosphorylated by ATR, regulates ATR expression, and is an essential component of the DNA damage checkpoint pathway. It localizes to the intranuclear foci after DNA damage or inhibition of replication.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATM and Rad3 related interacting protein; ATM and Rad3-related-interacting protein; ATR IP; ATR-interacting protein; DNase III; DRN3; FLJ12343
基因别名: 6620401K05Rik; AGS1; ATRIP
UniProt ID: (Human) Q8WXE1, (Mouse) Q8BMG1
Entrez Gene ID: (Human) 84126, (Mouse) 235610
